Comparison of two doses of recombinant human bone morphogenetic protein in absorbable collagen sponges for bone healing in dogs

To determine the effects of 2 doses of recombinant human bone morphogenetic protein-2 in an absorbable collagen sponge (rhBMP-2/ACS) on bone healing in dogs. 27 adult dogs. Dogs underwent a mid-diaphyseal (1-mm) tibial osteotomy (stabilized with external skeletal fixation) and received an ACS contai...

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Veröffentlicht in:	American journal of veterinary research 2007-08, Vol.68 (8), p.834-840
Hauptverfasser:	Schmiedt, C.W, Lu, Y, Heaney, K, Muir, P, Amodie, D.M, Markel, M.D
Format:	Artikel
Sprache:	eng
Schlagworte:	absorbable collagen sponges animal models Animals bone fractures bone morphogenetic proteins Bone Morphogenetic Proteins - administration & dosage Bone Morphogenetic Proteins - pharmacology Bone Morphogenetic Proteins - therapeutic use Collagen dogs dosage Dose-Response Relationship, Drug drug therapy fracture fixation Fracture Healing - drug effects Fractures, Bone - drug therapy growth factors histology Humans lameness pets radiography Recombinant Proteins Surgical Sponges tibia tissue repair
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