CCR5-Delta32 genetic polymorphism associated with benign clinical course and magnetic resonance imaging findings in Brazilian patients with multiple sclerosis

The CCR5 chemokine receptor has been implicated in the pathogenesis of multiple sclerosis (MS). This research was carried out to investigate the association between the CCR5-Delta32 deletion in 124 patients with MS from Southern Brazil. Ninety-eight (79.0%) patients presented with relapsing-remittin...

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Veröffentlicht in:	International journal of molecular medicine 2007-09, Vol.20 (3), p.337-344
Hauptverfasser:	Kaimen-Maciel, Damacio Ramón, Reiche, Edna Maria Vissoci, Brum Souza, Doralina Guimarães, Frota Comini, Elisabeth Regina, Bobroff, Flavio, Morimoto, Helena Kaminami, Ehara Watanabe, Maria Angélica, Carvalho De Oliveira, Jaqueline, Matsuo, Tiemi, Lopes, Josiane, Donadi, Eduardo Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age of Onset Aged Base Sequence Brazil Case-Control Studies DNA Primers - genetics Female Gene Frequency Genetic Markers Heterozygote Humans Magnetic Resonance Imaging Male Middle Aged Multiple Sclerosis - genetics Multiple Sclerosis - immunology Multiple Sclerosis - pathology Polymorphism, Genetic Prognosis Receptors, CCR5 - genetics Sequence Deletion
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