Recurrence of functional mitral regurgitation in patients with dilated cardiomyopathy undergoing mitral valve repair: how to predict it
Department of Cardiology and Cardiac Surgery, University G D'Annunzio, S Camillo de Lellis Hospital, via Forlanini 50, 66100 Chieti, Italy *Corresponding author. Tel.: +39-0871358628; fax: +39-0871357552. E-mail address : gabriele.digiammarco1{at}tin.it (G. Di Giammarco). This study was aimed...
Gespeichert in:
| Veröffentlicht in: | Interactive cardiovascular and thoracic surgery 2007-06, Vol.6 (3), p.340-344 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 344 |
|---|---|
| container_issue | 3 |
| container_start_page | 340 |
| container_title | Interactive cardiovascular and thoracic surgery |
| container_volume | 6 |
| creator | DiGiammarco, Gabriele Liberi, Roberta Giancane, Mirko Canosa, Carlo Gallina, Sabina Di Francesco, Alessandro Spira, Giuseppe Di Mauro, Michele |
| description | Department of Cardiology and Cardiac Surgery, University G D'Annunzio, S Camillo de Lellis Hospital, via Forlanini 50, 66100 Chieti, Italy
*Corresponding author. Tel.: +39-0871358628; fax: +39-0871357552. E-mail address : gabriele.digiammarco1{at}tin.it (G. Di Giammarco).
This study was aimed at identifying predictive variables for recurrence of mitral regurgitation (MR) in patients with dilated cardiomyopathy (DCM) undergoing mitral valve (MV) repair. From January 1997 to December 2005, 142 patients with DCM, 105 (73.9%) ischemic and 37 (26.1%) non-ischemic, underwent MV repair. Mean age was 66±10 years and mean MR grade was 3.2±0.7 (scale 1+ to 4+). Ninety-seven (71% ischemic, 29% non-ischemic), out of 98 still alive at follow-up, were included in this retrospective analysis. In all cases MV posterior annuloplasty was performed; all patients were followed-up by echocardiography (mean time interval of 44±28 months) to evaluate MR recurrence ( 2+/4+). Thirty-day mortality was 9.2% (13 patients). Mean MR grade at follow-up was 0.9±0.9. Four-year freedom from MR recurrence was 65.5%±8.3. Cox analysis showed left ventricular end-diastolic volume index (LVEDVi, OR=1.03, P =0.016, AUC=0.72), left ventricular end-systolic volume index (LVESVi, OR=1.03, P =0.033, AUC=0.71), left ventricular ejection fraction (LVEF, OR=0.82, P =0.001, AUC=0.72), mitral valve coaptation depth (MVCD, OR=1.6, P =0.017, AUC=0.72) to be predictive variables for MR recurrence. Preoperative left ventricular dilatation and function along with degree of papillary muscle displacement can be helpful in identifying patients with higher probability to undergo a durable MV repair.
Key Words: Functional mitral incompetence; Dilated cardiomyopathy; Valve surgery; Mitral annuloplasty |
| doi_str_mv | 10.1510/icvts.2006.146274 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68116212</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>68116212</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2884-3ca5217ed5e28ce2566d1faeb7a13c1fdc16b3d54523fac7a02f67413bcbe5273</originalsourceid><addsrcrecordid>eNpFkM9u1DAQhy0Eov94AC7IJ267eOzYSbihqlCkSpUqerYce5IYJXGwnV3tE_DaZNmFnmY085tvpI-Q98C2IIF98naX05YzprZQKF4Wr8glSFVval7J1__7WlyQq5R-MgY1E-wtuYBSqbpScEl-P6FdYsTJIg0tbZfJZh8mM9DR57iWiN0SO5_NcUz9ROe1wyknuve5p84PJqOj1kTnw3gI67o_0GVyGLvgp-4fZ2eGHa602fj4mfZhT3Ogc0TnbaY-35A3rRkSvjvXa_L89e7H7f3m4fHb99svDxvLq6rYCGskhxKdRF5Z5FIpB63BpjQgLLTOgmqEk4XkojW2NIy3qixANLZByUtxTT6euHMMvxZMWY8-WRwGM2FYklYVgOLA1yCcgjaGlCK2eo5-NPGggemjff3Xvj7a1yf7682HM3xpRnQvF2fdL9973_V7H1Gn0QzDGucnnNJCi4KJP8J8k1M</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68116212</pqid></control><display><type>article</type><title>Recurrence of functional mitral regurgitation in patients with dilated cardiomyopathy undergoing mitral valve repair: how to predict it</title><source>Oxford Journals Open Access Collection</source><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>DiGiammarco, Gabriele ; Liberi, Roberta ; Giancane, Mirko ; Canosa, Carlo ; Gallina, Sabina ; Di Francesco, Alessandro ; Spira, Giuseppe ; Di Mauro, Michele</creator><creatorcontrib>DiGiammarco, Gabriele ; Liberi, Roberta ; Giancane, Mirko ; Canosa, Carlo ; Gallina, Sabina ; Di Francesco, Alessandro ; Spira, Giuseppe ; Di Mauro, Michele</creatorcontrib><description>Department of Cardiology and Cardiac Surgery, University G D'Annunzio, S Camillo de Lellis Hospital, via Forlanini 50, 66100 Chieti, Italy
*Corresponding author. Tel.: +39-0871358628; fax: +39-0871357552. E-mail address : gabriele.digiammarco1{at}tin.it (G. Di Giammarco).
This study was aimed at identifying predictive variables for recurrence of mitral regurgitation (MR) in patients with dilated cardiomyopathy (DCM) undergoing mitral valve (MV) repair. From January 1997 to December 2005, 142 patients with DCM, 105 (73.9%) ischemic and 37 (26.1%) non-ischemic, underwent MV repair. Mean age was 66±10 years and mean MR grade was 3.2±0.7 (scale 1+ to 4+). Ninety-seven (71% ischemic, 29% non-ischemic), out of 98 still alive at follow-up, were included in this retrospective analysis. In all cases MV posterior annuloplasty was performed; all patients were followed-up by echocardiography (mean time interval of 44±28 months) to evaluate MR recurrence ( 2+/4+). Thirty-day mortality was 9.2% (13 patients). Mean MR grade at follow-up was 0.9±0.9. Four-year freedom from MR recurrence was 65.5%±8.3. Cox analysis showed left ventricular end-diastolic volume index (LVEDVi, OR=1.03, P =0.016, AUC=0.72), left ventricular end-systolic volume index (LVESVi, OR=1.03, P =0.033, AUC=0.71), left ventricular ejection fraction (LVEF, OR=0.82, P =0.001, AUC=0.72), mitral valve coaptation depth (MVCD, OR=1.6, P =0.017, AUC=0.72) to be predictive variables for MR recurrence. Preoperative left ventricular dilatation and function along with degree of papillary muscle displacement can be helpful in identifying patients with higher probability to undergo a durable MV repair.
Key Words: Functional mitral incompetence; Dilated cardiomyopathy; Valve surgery; Mitral annuloplasty</description><identifier>ISSN: 1569-9293</identifier><identifier>EISSN: 1569-9285</identifier><identifier>DOI: 10.1510/icvts.2006.146274</identifier><identifier>PMID: 17669861</identifier><language>eng</language><publisher>England: Eur Assoc Cardio Surg</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Cardiac Surgical Procedures - methods ; Cardiomyopathy, Dilated - complications ; Chi-Square Distribution ; Echocardiography ; Female ; Humans ; Male ; Middle Aged ; Mitral Valve Insufficiency - diagnostic imaging ; Mitral Valve Insufficiency - etiology ; Mitral Valve Insufficiency - mortality ; Mitral Valve Insufficiency - surgery ; Predictive Value of Tests ; Proportional Hazards Models ; Recurrence ; Statistics, Nonparametric ; Survival Analysis ; Treatment Outcome</subject><ispartof>Interactive cardiovascular and thoracic surgery, 2007-06, Vol.6 (3), p.340-344</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2884-3ca5217ed5e28ce2566d1faeb7a13c1fdc16b3d54523fac7a02f67413bcbe5273</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17669861$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>DiGiammarco, Gabriele</creatorcontrib><creatorcontrib>Liberi, Roberta</creatorcontrib><creatorcontrib>Giancane, Mirko</creatorcontrib><creatorcontrib>Canosa, Carlo</creatorcontrib><creatorcontrib>Gallina, Sabina</creatorcontrib><creatorcontrib>Di Francesco, Alessandro</creatorcontrib><creatorcontrib>Spira, Giuseppe</creatorcontrib><creatorcontrib>Di Mauro, Michele</creatorcontrib><title>Recurrence of functional mitral regurgitation in patients with dilated cardiomyopathy undergoing mitral valve repair: how to predict it</title><title>Interactive cardiovascular and thoracic surgery</title><addtitle>Interact Cardiovasc Thorac Surg</addtitle><description>Department of Cardiology and Cardiac Surgery, University G D'Annunzio, S Camillo de Lellis Hospital, via Forlanini 50, 66100 Chieti, Italy
*Corresponding author. Tel.: +39-0871358628; fax: +39-0871357552. E-mail address : gabriele.digiammarco1{at}tin.it (G. Di Giammarco).
This study was aimed at identifying predictive variables for recurrence of mitral regurgitation (MR) in patients with dilated cardiomyopathy (DCM) undergoing mitral valve (MV) repair. From January 1997 to December 2005, 142 patients with DCM, 105 (73.9%) ischemic and 37 (26.1%) non-ischemic, underwent MV repair. Mean age was 66±10 years and mean MR grade was 3.2±0.7 (scale 1+ to 4+). Ninety-seven (71% ischemic, 29% non-ischemic), out of 98 still alive at follow-up, were included in this retrospective analysis. In all cases MV posterior annuloplasty was performed; all patients were followed-up by echocardiography (mean time interval of 44±28 months) to evaluate MR recurrence ( 2+/4+). Thirty-day mortality was 9.2% (13 patients). Mean MR grade at follow-up was 0.9±0.9. Four-year freedom from MR recurrence was 65.5%±8.3. Cox analysis showed left ventricular end-diastolic volume index (LVEDVi, OR=1.03, P =0.016, AUC=0.72), left ventricular end-systolic volume index (LVESVi, OR=1.03, P =0.033, AUC=0.71), left ventricular ejection fraction (LVEF, OR=0.82, P =0.001, AUC=0.72), mitral valve coaptation depth (MVCD, OR=1.6, P =0.017, AUC=0.72) to be predictive variables for MR recurrence. Preoperative left ventricular dilatation and function along with degree of papillary muscle displacement can be helpful in identifying patients with higher probability to undergo a durable MV repair.
Key Words: Functional mitral incompetence; Dilated cardiomyopathy; Valve surgery; Mitral annuloplasty</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Cardiac Surgical Procedures - methods</subject><subject>Cardiomyopathy, Dilated - complications</subject><subject>Chi-Square Distribution</subject><subject>Echocardiography</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mitral Valve Insufficiency - diagnostic imaging</subject><subject>Mitral Valve Insufficiency - etiology</subject><subject>Mitral Valve Insufficiency - mortality</subject><subject>Mitral Valve Insufficiency - surgery</subject><subject>Predictive Value of Tests</subject><subject>Proportional Hazards Models</subject><subject>Recurrence</subject><subject>Statistics, Nonparametric</subject><subject>Survival Analysis</subject><subject>Treatment Outcome</subject><issn>1569-9293</issn><issn>1569-9285</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkM9u1DAQhy0Eov94AC7IJ267eOzYSbihqlCkSpUqerYce5IYJXGwnV3tE_DaZNmFnmY085tvpI-Q98C2IIF98naX05YzprZQKF4Wr8glSFVval7J1__7WlyQq5R-MgY1E-wtuYBSqbpScEl-P6FdYsTJIg0tbZfJZh8mM9DR57iWiN0SO5_NcUz9ROe1wyknuve5p84PJqOj1kTnw3gI67o_0GVyGLvgp-4fZ2eGHa602fj4mfZhT3Ogc0TnbaY-35A3rRkSvjvXa_L89e7H7f3m4fHb99svDxvLq6rYCGskhxKdRF5Z5FIpB63BpjQgLLTOgmqEk4XkojW2NIy3qixANLZByUtxTT6euHMMvxZMWY8-WRwGM2FYklYVgOLA1yCcgjaGlCK2eo5-NPGggemjff3Xvj7a1yf7682HM3xpRnQvF2fdL9973_V7H1Gn0QzDGucnnNJCi4KJP8J8k1M</recordid><startdate>20070601</startdate><enddate>20070601</enddate><creator>DiGiammarco, Gabriele</creator><creator>Liberi, Roberta</creator><creator>Giancane, Mirko</creator><creator>Canosa, Carlo</creator><creator>Gallina, Sabina</creator><creator>Di Francesco, Alessandro</creator><creator>Spira, Giuseppe</creator><creator>Di Mauro, Michele</creator><general>Eur Assoc Cardio Surg</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20070601</creationdate><title>Recurrence of functional mitral regurgitation in patients with dilated cardiomyopathy undergoing mitral valve repair: how to predict it</title><author>DiGiammarco, Gabriele ; Liberi, Roberta ; Giancane, Mirko ; Canosa, Carlo ; Gallina, Sabina ; Di Francesco, Alessandro ; Spira, Giuseppe ; Di Mauro, Michele</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2884-3ca5217ed5e28ce2566d1faeb7a13c1fdc16b3d54523fac7a02f67413bcbe5273</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Cardiac Surgical Procedures - methods</topic><topic>Cardiomyopathy, Dilated - complications</topic><topic>Chi-Square Distribution</topic><topic>Echocardiography</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mitral Valve Insufficiency - diagnostic imaging</topic><topic>Mitral Valve Insufficiency - etiology</topic><topic>Mitral Valve Insufficiency - mortality</topic><topic>Mitral Valve Insufficiency - surgery</topic><topic>Predictive Value of Tests</topic><topic>Proportional Hazards Models</topic><topic>Recurrence</topic><topic>Statistics, Nonparametric</topic><topic>Survival Analysis</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DiGiammarco, Gabriele</creatorcontrib><creatorcontrib>Liberi, Roberta</creatorcontrib><creatorcontrib>Giancane, Mirko</creatorcontrib><creatorcontrib>Canosa, Carlo</creatorcontrib><creatorcontrib>Gallina, Sabina</creatorcontrib><creatorcontrib>Di Francesco, Alessandro</creatorcontrib><creatorcontrib>Spira, Giuseppe</creatorcontrib><creatorcontrib>Di Mauro, Michele</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Interactive cardiovascular and thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DiGiammarco, Gabriele</au><au>Liberi, Roberta</au><au>Giancane, Mirko</au><au>Canosa, Carlo</au><au>Gallina, Sabina</au><au>Di Francesco, Alessandro</au><au>Spira, Giuseppe</au><au>Di Mauro, Michele</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recurrence of functional mitral regurgitation in patients with dilated cardiomyopathy undergoing mitral valve repair: how to predict it</atitle><jtitle>Interactive cardiovascular and thoracic surgery</jtitle><addtitle>Interact Cardiovasc Thorac Surg</addtitle><date>2007-06-01</date><risdate>2007</risdate><volume>6</volume><issue>3</issue><spage>340</spage><epage>344</epage><pages>340-344</pages><issn>1569-9293</issn><eissn>1569-9285</eissn><abstract>Department of Cardiology and Cardiac Surgery, University G D'Annunzio, S Camillo de Lellis Hospital, via Forlanini 50, 66100 Chieti, Italy
*Corresponding author. Tel.: +39-0871358628; fax: +39-0871357552. E-mail address : gabriele.digiammarco1{at}tin.it (G. Di Giammarco).
This study was aimed at identifying predictive variables for recurrence of mitral regurgitation (MR) in patients with dilated cardiomyopathy (DCM) undergoing mitral valve (MV) repair. From January 1997 to December 2005, 142 patients with DCM, 105 (73.9%) ischemic and 37 (26.1%) non-ischemic, underwent MV repair. Mean age was 66±10 years and mean MR grade was 3.2±0.7 (scale 1+ to 4+). Ninety-seven (71% ischemic, 29% non-ischemic), out of 98 still alive at follow-up, were included in this retrospective analysis. In all cases MV posterior annuloplasty was performed; all patients were followed-up by echocardiography (mean time interval of 44±28 months) to evaluate MR recurrence ( 2+/4+). Thirty-day mortality was 9.2% (13 patients). Mean MR grade at follow-up was 0.9±0.9. Four-year freedom from MR recurrence was 65.5%±8.3. Cox analysis showed left ventricular end-diastolic volume index (LVEDVi, OR=1.03, P =0.016, AUC=0.72), left ventricular end-systolic volume index (LVESVi, OR=1.03, P =0.033, AUC=0.71), left ventricular ejection fraction (LVEF, OR=0.82, P =0.001, AUC=0.72), mitral valve coaptation depth (MVCD, OR=1.6, P =0.017, AUC=0.72) to be predictive variables for MR recurrence. Preoperative left ventricular dilatation and function along with degree of papillary muscle displacement can be helpful in identifying patients with higher probability to undergo a durable MV repair.
Key Words: Functional mitral incompetence; Dilated cardiomyopathy; Valve surgery; Mitral annuloplasty</abstract><cop>England</cop><pub>Eur Assoc Cardio Surg</pub><pmid>17669861</pmid><doi>10.1510/icvts.2006.146274</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1569-9293 |
| ispartof | Interactive cardiovascular and thoracic surgery, 2007-06, Vol.6 (3), p.340-344 |
| issn | 1569-9293 1569-9285 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68116212 |
| source | Oxford Journals Open Access Collection; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adult Aged Aged, 80 and over Cardiac Surgical Procedures - methods Cardiomyopathy, Dilated - complications Chi-Square Distribution Echocardiography Female Humans Male Middle Aged Mitral Valve Insufficiency - diagnostic imaging Mitral Valve Insufficiency - etiology Mitral Valve Insufficiency - mortality Mitral Valve Insufficiency - surgery Predictive Value of Tests Proportional Hazards Models Recurrence Statistics, Nonparametric Survival Analysis Treatment Outcome |
| title | Recurrence of functional mitral regurgitation in patients with dilated cardiomyopathy undergoing mitral valve repair: how to predict it |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-21T14%3A48%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Recurrence%20of%20functional%20mitral%20regurgitation%20in%20patients%20with%20dilated%20cardiomyopathy%20undergoing%20mitral%20valve%20repair:%20how%20to%20predict%20it&rft.jtitle=Interactive%20cardiovascular%20and%20thoracic%20surgery&rft.au=DiGiammarco,%20Gabriele&rft.date=2007-06-01&rft.volume=6&rft.issue=3&rft.spage=340&rft.epage=344&rft.pages=340-344&rft.issn=1569-9293&rft.eissn=1569-9285&rft_id=info:doi/10.1510/icvts.2006.146274&rft_dat=%3Cproquest_cross%3E68116212%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=68116212&rft_id=info:pmid/17669861&rfr_iscdi=true |