Effects of Stimulant Medication on Growth Rates Across 3 Years in the MTA Follow-up

ABSTRACT Objective: To evaluate the hypothesis of stimulant medication effect on physical growth in the follow-up phase of the Multimodal Treatment Study of Children With ADHD. Method: Naturalistic subgroups were established based on patterns of treatment with stimulant medication at baseline, 14-,...

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Veröffentlicht in:	Journal of the American Academy of Child and Adolescent Psychiatry 2007-08, Vol.46 (8), p.1015-1027
Hauptverfasser:	SWANSON, JAMES M., Ph.D, ELLIOTT, GLEN R., Ph.D., M.D, GREENHILL, LAURENCE L., M.D, WIGAL, TIMOTHY, Ph.D, ARNOLD, L. EUGENE, M.D, VITIELLO, BENEDETTO, M.D, HECHTMAN, LILY, M.D, EPSTEIN, JEFFERY N., Ph.D, PELHAM, WILLIAM E., Ph.D, ABIKOFF, HOWARD B., Ph.D, NEWCORN, JEFFREY H., M.D, MOLINA, BROOKE S.G., Ph.D, HINSHAW, STEPHEN P., Ph.D, WELLS, KAREN C., Ph.D, HOZA, BETSY, Ph.D, JENSEN, PETER S., M.D, GIBBONS, ROBERT D., Ph.D, HUR, KWAN, Ph.D, STEHLI, ANNAMARIE, M.P.H, DAVIES, MARK, M.S, MARCH, JOHN S., M.D., M.P.H, CONNERS, C. KEITH, Ph.D, CARON, MARK, Ph.D, VOLKOW, NORA D., M.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Attention Deficit Disorder with Hyperactivity - diagnosis Attention Deficit Disorder with Hyperactivity - drug therapy Attention Deficit Disorder with Hyperactivity - therapy Attention Deficit Hyperactivity Disorder Behavior Therapy - methods Central Nervous System Stimulants - therapeutic use Child Child Development Children Clinical outcomes Clinical trials Combined Modality Therapy Comparative Analysis Drug Therapy Evaluation Methods Female Follow-Up Studies growth Growth rate Humans Interaction long-term outcome Male methylphenidate Norms Outcomes of Treatment Pediatrics Physical growth Psychiatry Science Education Severity of Illness Index side effects Statistical Analysis Stimulants Stimuli Time Factors Treatment methods
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Zusammenfassung:	ABSTRACT Objective: To evaluate the hypothesis of stimulant medication effect on physical growth in the follow-up phase of the Multimodal Treatment Study of Children With ADHD. Method: Naturalistic subgroups were established based on patterns of treatment with stimulant medication at baseline, 14-, 24-, and 36-month assessments: not medicated ( n = 65), newly medicated ( n = 88), consistently medicated ( n = 70), and inconsistently medicated ( n = 147). Analysis of variance was used to evaluate effects of subgroup and assessment time on measures of relative size ( z scores) obtained from growth norms. Results: The subgroup × assessment time interaction was significant for z height ( p
ISSN:	0890-8567 1527-5418
DOI:	10.1097/chi.0b013e3180686d7e