Functional analysis of Trypanosoma brucei PUF1

The genomes of Trypanosoma brucei, Leishmania major and Trypanosoma cruzi each encode 10 proteins with PUF domains. PUF domain proteins from yeast and metazoa have been shown to bind RNA and to regulate mRNA stability and translation. Phylogenetic analysis suggested that the PUF proteins were duplic...

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Veröffentlicht in:	Molecular and biochemical parasitology 2006-12, Vol.150 (2), p.340-349
Hauptverfasser:	Luu, Van-Duc, Brems, Stefanie, Hoheisel, Jörg D., Burchmore, Richard, Guilbride, D. Lys, Clayton, Christine
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Carrier Proteins - chemistry Carrier Proteins - genetics Carrier Proteins - physiology Leishmania major Metazoa Oligonucleotide Array Sequence Analysis Phylogeny Polyribosomes - metabolism Proteome Proteomics Protozoan Proteins - chemistry Protozoan Proteins - genetics Protozoan Proteins - physiology PUF Pumilio Transcriptome Transfection Trypanosoma brucei Trypanosoma brucei brucei - genetics Trypanosoma brucei brucei - growth & development Trypanosoma brucei brucei - physiology Trypanosoma cruzi
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