Transfer of accelerated presbycusis by transplantation of bone marrow cells from senescence-accelerated mice

Until now, there has been no effective therapy for chronic sensorineural hearing impairment. This study investigated the role of bone marrow cells (BMCs) in cochlear dysfunction. BALB/c mice (2 months of age), a non-presbycusis-prone mouse strain, were lethally irradiated and then transplanted with...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain research 2006-11, Vol.1120 (1), p.93-99
Hauptverfasser:	Baba, Susumu, Iwai, Hiroshi, Inaba, Muneo, Kawamoto, Kohei, Omae, Mariko, Yamashita, Toshio, Ikehara, Susumu
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - genetics Allogeneic bone marrow transplantation Animals BALB 3T3 Cells Biological and medical sciences Bone Marrow Transplantation - immunology Bone Marrow Transplantation - methods Cell Count Degeneration Disease Models, Animal Ear and associated structures. Auditory pathways and centers. Hearing. Vocal organ. Phonation. Sound production. Echolocation Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology Evoked Potentials, Auditory, Brain Stem - physiology Fluorescent Antibody Technique - methods Fundamental and applied biological sciences. Psychology Hearing Loss, Sensorineural - genetics Immune dysfunction Medical sciences Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Mutant Strains Nerve Degeneration - genetics Nerve Degeneration - pathology Non tumoral diseases Otorhinolaryngology. Stomatology Presbycusis Presbycusis - etiology Presbycusis - immunology Presbycusis - pathology Presbycusis - physiopathology Radiation Chimera Spiral Ganglion - immunology Spiral Ganglion - pathology Spiral Ganglion - physiopathology Spiral ganglion cell Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!