Identification of a Filamin Docking Site on PTP-PEST

PTP-PEST is a cytoplasmic protein-tyrosine phosphatase (PTP) implicated in the regulation of biological processes such as cell motility, cytokinesis, focal adhesion disassembly, and lymphocyte activation. Using a proteomics approach, filamin-A was identified as a novel interacting protein that bound...

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Veröffentlicht in:	The Journal of biological chemistry 2006-11, Vol.281 (45), p.34104-34112
Hauptverfasser:	Playford, Martin P., Lyons, Patrick D., Sastry, Sarita K., Schaller, Michael D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Blotting, Western Cell Nucleus - ultrastructure Cells, Cultured Contractile Proteins - metabolism Cytokinesis Filamins Flow Cytometry Glutathione Transferase - genetics Glutathione Transferase - metabolism Humans Kidney - cytology Kidney - metabolism Microfilament Proteins - metabolism Microscopy, Fluorescence Phenotype Protein Binding Protein Tyrosine Phosphatase, Non-Receptor Type 12 Protein Tyrosine Phosphatases - metabolism Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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