Induction of immunosuppressive functions of dendritic cells in vivo by CD4+CD25+ regulatory T cells: Role of B7‐H3 expression and antigen presentation

Suppressive functions of CD4+CD25+ regulatory T cells (Treg) are mainly studied by their interaction with conventional T cells. However, there is evidence that Treg also interact with antigen‐presenting cells (APC), leading to suppression of APC function in in vitro coculture systems. Studying the i...

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Veröffentlicht in:	European Journal of Immunology 2007-08, Vol.37 (8), p.2117-2126
Hauptverfasser:	Mahnke, Karsten, Ring, Sabine, Johnson, Theron S., Schallenberg, Sonja, Schönfeld, Kurt, Storn, Volker, Bedke, Tanja, Enk, Alexander H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen presentation Antigen Presentation - immunology B7 Antigens B7-1 Antigen - immunology CD4 Antigens - immunology Cell Communication - immunology Coculture Techniques Dendritic cells Dendritic Cells - immunology Flow Cytometry Interleukin-10 - immunology Interleukin-2 Receptor alpha Subunit - immunology Lymphocyte Activation - immunology Mice T cells T-Lymphocytes, Regulatory - immunology
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