Induction of leukemic-cell-specific cytotoxic T lymphocytes by autologous monocyte-derived dendritic cells presenting leukemic cell antigens

Leukemic‐dendritic cells (leukemic‐DCs) have certain limitations, which include difficult generation in 30–40% of patients, and low levels of expression of several key molecules. Therefore, an alternative approach using monocyte‐derived DCs pulsed with tumor antigens is required. We investigated the...

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Veröffentlicht in:	Journal of clinical apheresis 2006-10, Vol.21 (3), p.188-194
Hauptverfasser:	Lee, J.-J., Park, M.-S., Park, J.-S., Kang, H.-K., Kim, S.-K., Nguyen Pham, T.-N., Zhu, X.-W., Cho, D., Nam, J.-H., Kim, Y.-J., Rhee, J.-H., Chung, I.-J., Kim, H.-J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antigens, Neoplasm - chemistry Antigens, Neoplasm - metabolism Apoptosis Biological and medical sciences Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Bone marrow, stem cells transplantation. Graft versus host reaction Cell Separation dendritic cells Dendritic Cells - cytology Emergency and intensive care: renal failure. Dialysis management Flow Cytometry Humans Intensive care medicine Interferon-gamma - metabolism leukemia Leukemia - immunology Leukemia - metabolism leukemic cell antigens Leukocytes, Mononuclear - metabolism Lymphocyte Culture Test, Mixed Lymphocytes - metabolism Medical sciences monocyte Monocytes - cytology Monocytes - metabolism Phenotype T-Lymphocytes, Cytotoxic - cytology T-Lymphocytes, Cytotoxic - metabolism Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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