Rapid Screening of Doping Agents in Human Urine by Vacuum MALDI-Linear Ion Trap Mass Spectrometry

Detection of doping agents in urine frequently requires extensive separation prior to chemical analyses. Gas or liquid chromatography coupled to mass spectrometry has produced accurate and sensitive assays, but chromatographic separations require time and, sometimes, chemical derivatization. To avoi...

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Veröffentlicht in:	Analytical chemistry (Washington) 2007-08, Vol.79 (15), p.6020-6026
Hauptverfasser:	Kosanam, Hari, Sai Prakash, P. K, Yates, C. R, Miller, D. D, Ramagiri, Suma
Format:	Artikel
Sprache:	eng
Schlagworte:	Anabolic Agents - urine Analytical chemistry Benzoates - chemistry Betamethasone - urine Chemistry Chromatographic methods and physical methods associated with chromatography Chromatography Coumaric Acids - chemistry Doping in Sports Exact sciences and technology Fatty Alcohols Gas chromatographic methods Humans Mass spectrometry Matrix Nandrolone - urine Other chromatographic methods Porphyrins - chemistry Quaternary Ammonium Compounds - chemistry Reproducibility of Results Sensitivity and Specificity Spectrometric and optical methods Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods Substance Abuse Detection - methods Surface-Active Agents - chemistry Testosterone - analogs & derivatives Testosterone - urine Trenbolone Acetate - urine Urine Vacuum
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