Pharmacokinetics of a single intravenous dose of marbofloxacin in adult donkeys

Six donkeys each received 2 mg/kg marbofloxacin as a 10 per cent aqueous solution administered intravenously. Principal pharmacokinetic parameters were determined and two efficacy indices were computed by using pharmacokinetic parameters and selected mic90 values of marbofloxacin against pathogenic...

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Veröffentlicht in:	Veterinary record 2007-07, Vol.161 (4), p.133-136
Hauptverfasser:	González, F., Rodríguez, C., De Lucas, J. J., Waxman, S., San Andrés, M. D., Serres, C., Nieto, J., San Andrés, M. I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - pharmacokinetics antimicrobial agents Area Under Curve asses Bacterial Infections - drug therapy Bacterial Infections - metabolism Bacterial Infections - veterinary Equidae - blood Equidae - metabolism Female Fluoroquinolones - pharmacokinetics Half-Life Horse Diseases - drug therapy Horse Diseases - metabolism Horses - blood Horses - metabolism Injections, Intravenous - veterinary Male marbofloxacin Metabolic Clearance Rate pharmacokinetics Quinolones - pharmacokinetics Species Specificity Treatment Outcome
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