2-Thioindoles as Precursors to Spiro-Fused Indolines: Synthesis of (±)-Dehaloperophoramidine
Closing the ring: The cyclization of a 2‐thioindole with an electrophilic substituent serves as the key transformation in a synthetic strategy for the generation of indole alkaloids of the perophoramidine and communesin class. DBU=1,8‐diazabicyclo[5.4.0]undec‐7‐ene, Ms=methanesulfonyl chloride....
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| Veröffentlicht in: | Angewandte Chemie International Edition 2006-06, Vol.45 (26), p.4317-4320 |
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| container_issue | 26 |
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| container_title | Angewandte Chemie International Edition |
| container_volume | 45 |
| creator | Sabahi, Amir Novikov, Alexei Rainier, Jon D. |
| description | Closing the ring: The cyclization of a 2‐thioindole with an electrophilic substituent serves as the key transformation in a synthetic strategy for the generation of indole alkaloids of the perophoramidine and communesin class. DBU=1,8‐diazabicyclo[5.4.0]undec‐7‐ene, Ms=methanesulfonyl chloride. |
| doi_str_mv | 10.1002/anie.200601278 |
| format | Article |
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| ispartof | Angewandte Chemie International Edition, 2006-06, Vol.45 (26), p.4317-4320 |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | communesin Crystallography, X-Ray Cyclization Heterocyclic Compounds, 4 or More Rings - chemistry Hydrocarbons, Halogenated - chemistry Indoles - chemistry Models, Molecular Molecular Structure natural products perophoramidine Sulfhydryl Compounds - chemistry thioindoles |
| title | 2-Thioindoles as Precursors to Spiro-Fused Indolines: Synthesis of (±)-Dehaloperophoramidine |
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