Effect of hepatocyte growth factor on endogenous hepatocarcinogenesis in rats fed a choline-deficient L-amino acid-defined diet

Hepatocyte growth factor (HGF) is a promising agent for the treatment of intractable liver disease, due to its mitogenic, anti-apoptotic, and anti-fibrotic effects. We investigated the effect of recombinant human HGF (rh-HGF) on the development of both hepatocellular carcinoma (HCC) and preneoplasti...

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Veröffentlicht in:	Oncology reports 2006-07, Vol.16 (1), p.25-31
Hauptverfasser:	NAKANISHI, Chihiro, MORIUCHI, Akihiro, UTO, Hirofumi, KATAOKA, Hiroaki, TSUBOUCHI, Hirohito, IDO, Akio, NUMATA, Masatsugu, KIM, Il-Deok, KUSUMOTO, Kazunori, HASUIKE, Satoru, ABE, Hiroo, NAGATA, Kenji, AKIYAMA, Yutaka
Format:	Artikel
Sprache:	eng
Schlagworte:	Albumins - metabolism Amino Acids - metabolism Animal Feed Animals Biological and medical sciences Choline - metabolism Gastroenterology. Liver. Pancreas. Abdomen Hepatocyte Growth Factor - metabolism Hepatocyte Growth Factor - physiology Humans Liver Neoplasms - etiology Liver Neoplasms - metabolism Liver. Biliary tract. Portal circulation. Exocrine pancreas Lung Neoplasms - secondary Male Medical sciences Neoplasm Metastasis Rats Rats, Inbred F344 Recombinant Proteins - metabolism Tumors
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