Prevalence of Actinic Keratoses and Associated Factors in a Representative Sample of the Italian Adult Population: Results From the Prevalence of Actinic Keratoses Italian Study, 2003-2004

OBJECTIVE The Prevalence of Actinic Keratoses Italian Study (PraKtis) was designed to estimate the point prevalence of actinic keratoses (AKs) and associated factors in a representative sample of the Italian adult population. DESIGN A representative sample of people 45 years or older was selected fr...

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Veröffentlicht in:Archives of dermatology (1960) 2006-06, Vol.142 (6), p.722-726
Hauptverfasser: Naldi, Luigi, Chatenoud, Liliane, Piccitto, Roberto, Colombo, Paolo, Placchesi, Elena Benedetti, La Vecchia, Carlo
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container_issue 6
container_start_page 722
container_title Archives of dermatology (1960)
container_volume 142
creator Naldi, Luigi
Chatenoud, Liliane
Piccitto, Roberto
Colombo, Paolo
Placchesi, Elena Benedetti
La Vecchia, Carlo
description OBJECTIVE The Prevalence of Actinic Keratoses Italian Study (PraKtis) was designed to estimate the point prevalence of actinic keratoses (AKs) and associated factors in a representative sample of the Italian adult population. DESIGN A representative sample of people 45 years or older was selected from the electoral rolls according to a stratified random sampling design. SETTING A total of 180 specifically trained interviewers contacted the sampled subjects and conducted face-to-face, computer-assisted interviews and skin assessments. PARTICIPANTS A total of 12 483 subjects contacted and interviewed from March 1, 2003, through April 30, 2004. MAIN OUTCOME MEASURES History of AKs and evidence of AKs at the interview. RESULTS Overall, an estimated 34% of the Italian population reported ever having undergone a dermatological examination. A history of AKs was reported by 0.3% of the total sample. Topical therapy was the most popular treatment according to 39% of subjects, whereas 25% reported that they did not receive therapy. Based on the interviewer's judgment, the point prevalence of AKs was 1.4% (95% confidence interval, 1.2%-1.8%). Forty-two percent of people with AKs were unaware of their condition. The prevalence was higher among men than women and increased steadily with age. The prevalence increased with lighter phenotype and with more severe facial wrinkling. It also increased with the reported number of hours spent in the sun during the week and on holidays. No clear variation was observed according to the reported use of sunscreens. Lesions were usually multiple (median number, 4). There was a strong association between a history of nonmelanoma skin cancers and the presence of AKs (odds ratio, 4.5; 95% confidence interval, 1.8-11.0). CONCLUSIONS The prevalence of AKs in our study was remarkably lower than expected based on data from the United States and Australia; in Italy, AKs seem to be underdiagnosed and undertreated.Arch Dermatol. 2006;142:722-726-->
doi_str_mv 10.1001/archderm.142.6.722
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DESIGN A representative sample of people 45 years or older was selected from the electoral rolls according to a stratified random sampling design. SETTING A total of 180 specifically trained interviewers contacted the sampled subjects and conducted face-to-face, computer-assisted interviews and skin assessments. PARTICIPANTS A total of 12 483 subjects contacted and interviewed from March 1, 2003, through April 30, 2004. MAIN OUTCOME MEASURES History of AKs and evidence of AKs at the interview. RESULTS Overall, an estimated 34% of the Italian population reported ever having undergone a dermatological examination. A history of AKs was reported by 0.3% of the total sample. Topical therapy was the most popular treatment according to 39% of subjects, whereas 25% reported that they did not receive therapy. Based on the interviewer's judgment, the point prevalence of AKs was 1.4% (95% confidence interval, 1.2%-1.8%). Forty-two percent of people with AKs were unaware of their condition. The prevalence was higher among men than women and increased steadily with age. The prevalence increased with lighter phenotype and with more severe facial wrinkling. It also increased with the reported number of hours spent in the sun during the week and on holidays. No clear variation was observed according to the reported use of sunscreens. Lesions were usually multiple (median number, 4). There was a strong association between a history of nonmelanoma skin cancers and the presence of AKs (odds ratio, 4.5; 95% confidence interval, 1.8-11.0). 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DESIGN A representative sample of people 45 years or older was selected from the electoral rolls according to a stratified random sampling design. SETTING A total of 180 specifically trained interviewers contacted the sampled subjects and conducted face-to-face, computer-assisted interviews and skin assessments. PARTICIPANTS A total of 12 483 subjects contacted and interviewed from March 1, 2003, through April 30, 2004. MAIN OUTCOME MEASURES History of AKs and evidence of AKs at the interview. RESULTS Overall, an estimated 34% of the Italian population reported ever having undergone a dermatological examination. A history of AKs was reported by 0.3% of the total sample. Topical therapy was the most popular treatment according to 39% of subjects, whereas 25% reported that they did not receive therapy. Based on the interviewer's judgment, the point prevalence of AKs was 1.4% (95% confidence interval, 1.2%-1.8%). Forty-two percent of people with AKs were unaware of their condition. The prevalence was higher among men than women and increased steadily with age. The prevalence increased with lighter phenotype and with more severe facial wrinkling. It also increased with the reported number of hours spent in the sun during the week and on holidays. No clear variation was observed according to the reported use of sunscreens. Lesions were usually multiple (median number, 4). There was a strong association between a history of nonmelanoma skin cancers and the presence of AKs (odds ratio, 4.5; 95% confidence interval, 1.8-11.0). 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Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of dermatology (1960)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Naldi, Luigi</au><au>Chatenoud, Liliane</au><au>Piccitto, Roberto</au><au>Colombo, Paolo</au><au>Placchesi, Elena Benedetti</au><au>La Vecchia, Carlo</au><aucorp>Prevalence of Actinic Keratoses Italian Study (PraKtis) Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of Actinic Keratoses and Associated Factors in a Representative Sample of the Italian Adult Population: Results From the Prevalence of Actinic Keratoses Italian Study, 2003-2004</atitle><jtitle>Archives of dermatology (1960)</jtitle><addtitle>Arch Dermatol</addtitle><date>2006-06-01</date><risdate>2006</risdate><volume>142</volume><issue>6</issue><spage>722</spage><epage>726</epage><pages>722-726</pages><issn>0003-987X</issn><issn>2168-6068</issn><eissn>1538-3652</eissn><eissn>2168-6084</eissn><coden>ARDEAC</coden><abstract>OBJECTIVE The Prevalence of Actinic Keratoses Italian Study (PraKtis) was designed to estimate the point prevalence of actinic keratoses (AKs) and associated factors in a representative sample of the Italian adult population. DESIGN A representative sample of people 45 years or older was selected from the electoral rolls according to a stratified random sampling design. SETTING A total of 180 specifically trained interviewers contacted the sampled subjects and conducted face-to-face, computer-assisted interviews and skin assessments. PARTICIPANTS A total of 12 483 subjects contacted and interviewed from March 1, 2003, through April 30, 2004. MAIN OUTCOME MEASURES History of AKs and evidence of AKs at the interview. RESULTS Overall, an estimated 34% of the Italian population reported ever having undergone a dermatological examination. A history of AKs was reported by 0.3% of the total sample. Topical therapy was the most popular treatment according to 39% of subjects, whereas 25% reported that they did not receive therapy. Based on the interviewer's judgment, the point prevalence of AKs was 1.4% (95% confidence interval, 1.2%-1.8%). Forty-two percent of people with AKs were unaware of their condition. The prevalence was higher among men than women and increased steadily with age. The prevalence increased with lighter phenotype and with more severe facial wrinkling. It also increased with the reported number of hours spent in the sun during the week and on holidays. No clear variation was observed according to the reported use of sunscreens. Lesions were usually multiple (median number, 4). There was a strong association between a history of nonmelanoma skin cancers and the presence of AKs (odds ratio, 4.5; 95% confidence interval, 1.8-11.0). CONCLUSIONS The prevalence of AKs in our study was remarkably lower than expected based on data from the United States and Australia; in Italy, AKs seem to be underdiagnosed and undertreated.Arch Dermatol. 2006;142:722-726--&gt;</abstract><cop>Chicago, IL</cop><pub>American Medical Association</pub><pmid>16785374</pmid><doi>10.1001/archderm.142.6.722</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
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source MEDLINE; American Medical Association Journals
subjects Age Factors
Aged
Biological and medical sciences
Confidence intervals
Data analysis
Data collection
Dermatology
Dyskeratosis
Estimates
European Continental Ancestry Group - statistics & numerical data
Female
Genotype & phenotype
Humans
Interviews
Interviews as Topic
Italy - epidemiology
Keratosis - epidemiology
Keratosis - ethnology
Keratosis - etiology
Male
Medical sciences
Medical treatment
Middle Aged
Prevalence
Risk
Sex Factors
Skin cancer
Skin Neoplasms - epidemiology
Skin Neoplasms - ethnology
Skin Neoplasms - etiology
Sunlight - adverse effects
title Prevalence of Actinic Keratoses and Associated Factors in a Representative Sample of the Italian Adult Population: Results From the Prevalence of Actinic Keratoses Italian Study, 2003-2004
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