Epigenetics: Behavioral Influences on Gene Function, Part II: Molecular Mechanisms
Differences arise in the emotional, maternal, and cognitive behaviors that result from early maternal influences. The influences on emotional behavior appear to be mediated by reactivity in the hypothalamicpituitary-adrenal axis. Here in the second and last part of a series about behavioral influenc...
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| Veröffentlicht in: | Journal of the American Academy of Child and Adolescent Psychiatry 2008-04, Vol.47 (4), p.374-378 |
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| container_end_page | 378 |
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| container_issue | 4 |
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| container_title | Journal of the American Academy of Child and Adolescent Psychiatry |
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| creator | OGREN, MARILEE P., Ph.D LOMBROSO, PAUL J., M.D |
| description | Differences arise in the emotional, maternal, and cognitive behaviors that result from early maternal influences. The influences on emotional behavior appear to be mediated by reactivity in the hypothalamicpituitary-adrenal axis. Here in the second and last part of a series about behavioral influence on gene function, Ogren and Lombroso describe the molecular mechanisms thought to be responsible for the differences in the adult offspring, as well as the molecular mechanisms by which epigenetic effects are propagated from one generation to the next. |
| doi_str_mv | 10.1097/CHI.0b013e318165f163 |
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The influences on emotional behavior appear to be mediated by reactivity in the hypothalamicpituitary-adrenal axis. 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The influences on emotional behavior appear to be mediated by reactivity in the hypothalamicpituitary-adrenal axis. 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| subjects | Animals Arousal - genetics Arousal - physiology Behavior Behaviour Biological and medical sciences Brain Child clinical studies DNA Damage - physiology Emotions Epigenesis, Genetic - genetics Estrogen Receptor alpha - genetics Female Frontal Lobe - physiopathology Gene Expression Regulation - genetics Gene Expression Regulation - physiology Genes Hippocampus - physiopathology Humans Hydrocortisone - blood Hypothalamo-Hypophyseal System - physiopathology Influence Maternal Behavior - physiology Maternal Behavior - psychology Maternal characteristics Medical sciences Memories Mental Disorders - genetics Mental Disorders - physiopathology Mental Disorders - psychology Mother-Child Relations Neonatal care Neuronal Plasticity - genetics Neuronal Plasticity - physiology Parents & parenting Pediatrics Phenotype Pituitary-Adrenal System - physiopathology Prenatal care Preoptic Area - physiopathology Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Rats Receptors, Glucocorticoid - genetics Social Environment Up-Regulation - genetics |
| title | Epigenetics: Behavioral Influences on Gene Function, Part II: Molecular Mechanisms |
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