High resolution mapping of chromosomal regions controlling resistance to gastrointestinal nematode infections in an advanced intercross line of mice

Fine mapping of quantitative trait loci (QTL) associated with resistance to the gastrointestinal parasite Heligmosomoides polygyrus was achieved on F(6)/F(7) offspring (1076 mice) from resistant (SWR) and susceptible (CBA) mouse strains by selective genotyping (top and bottom 20% selected on total w...

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Veröffentlicht in:	Mammalian genome 2006-06, Vol.17 (6), p.584-597
Hauptverfasser:	Behnke, Jerzy M, Iraqi, Fuad A, Mugambi, John M, Clifford, Simon, Nagda, Sonal, Wakelin, Derek, Kemp, Stephen J, Baker, R Leyden, Gibson, John P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell size Chromosome 1 Chromosome 17 Confidence intervals Crosses, Genetic Gastrointestinal Tract - parasitology Gene mapping Genomes Genomics Genotyping Granuloma Immune response Immunity, Innate - genetics Immunoglobulin E Immunoglobulin G Major histocompatibility complex Mice Mice, Inbred CBA Mucosa Nematoda Nematospiroides dubius - immunology Parasite resistance Pest resistance Physical Chromosome Mapping - methods Quantitative Trait Loci Strongylida Infections - genetics Strongylida Infections - immunology
Online-Zugang:	Volltext
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