Optimizing UV laser focus profiles for improved MALDI performance

Matrix assisted laser desorption/ionization (MALDI) applications, such as proteomics, genomics, clinical profiling and MALDI imaging, have created a growing demand for faster instrumentation. Since the commonly used nitrogen lasers have throughput and life span limitations, diode‐pumped solid‐state...

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Veröffentlicht in:	Journal of mass spectrometry. 2006-06, Vol.41 (6), p.705-716
Hauptverfasser:	Holle, Armin, Haase, Andreas, Kayser, Markus, Höhndorf, Jens
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms beam profile Exact sciences and technology Instruments, apparatus, components and techniques common to several branches of physics and astronomy laser Lasers MALDI MALDI imaging Mass spectrometers and related techniques Physics Reproducibility of Results Scattering, Radiation Sensitivity and Specificity smart beam solid state Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods thin-layer preparation Ultraviolet Rays YAG
Online-Zugang:	Volltext
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