Design and development of polymers for gene delivery

Key Points Human gene therapy utilizes genetic material – DNA or RNA – as a therapeutic for genetic, acquired and infectious diseases. Gene therapy's potential is great, but the lack of safe and efficient gene delivery methods is a limiting obstacle to clinical implementation. Gene delivery met...

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Veröffentlicht in:	Nature reviews. Drug discovery 2005-07, Vol.4 (7), p.581-593
Hauptverfasser:	Pack, Daniel W, Hoffman, Allan S, Pun, Suzie, Stayton, Patrick S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Biopolymers Biotechnology Cancer Research Cyclodextrins Drug Design Gene therapy Gene Transfer Techniques Genetic engineering Genetic Therapy Genetic Vectors Humans Imidazoles - chemistry Medicinal Chemistry Methods Molecular Medicine Pharmacology/Toxicology Physiological aspects Polymers review-article Vectors (Biology)
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