Disrupted compartmental organization of axons and dendrites within olfactory glomeruli of mice deficient in the olfactory cell adhesion molecule, OCAM

There is an overall topographic connectivity in the axonal projections of olfactory sensory neurons from the olfactory epithelium (OE) to the olfactory bulb (OB). The molecular determinants of this overall topographic OE–OB connectivity are not known. For 20 years, the intriguing expression pattern...

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Veröffentlicht in:	Molecular and cellular neuroscience 2006-05, Vol.32 (1), p.1-14
Hauptverfasser:	Walz, Andreas, Mombaerts, Peter, Greer, Charles A., Treloar, Helen B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Axon guidance Axons - metabolism Axons - ultrastructure Cell Communication - genetics Cell Differentiation - genetics Dendrites - metabolism Dendrites - ultrastructure Female Gene Expression Regulation, Developmental - genetics Male Mice Mice, Inbred C57BL Mice, Knockout Mice, Transgenic Neural Cell Adhesion Molecules - deficiency Neural Cell Adhesion Molecules - genetics Neuronal Plasticity - genetics Neuropil - metabolism Neuropil - ultrastructure Odor Olfaction Olfactory bulb Olfactory Bulb - abnormalities Olfactory Bulb - cytology Olfactory Bulb - metabolism Olfactory Nerve - abnormalities Olfactory Nerve - cytology Olfactory Nerve - metabolism Olfactory Receptor Neurons - abnormalities Olfactory Receptor Neurons - cytology Olfactory Receptor Neurons - metabolism Plasticity Presynaptic Terminals - metabolism Presynaptic Terminals - ultrastructure Smell Smell - genetics
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