Functional coordination of intraflagellar transport motors

Cilia have diverse roles in motility and sensory reception, and defects in cilia function contribute to ciliary diseases such as Bardet–Biedl syndrome (BBS). Intraflagellar transport (IFT) motors assemble and maintain cilia by transporting ciliary precursors, bound to protein complexes called IFT pa...

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Veröffentlicht in:	Nature (London) 2005-07, Vol.436 (7050), p.583-587
Hauptverfasser:	Ou, Guangshuo, E. Blacque, Oliver, Snow, Joshua J., Leroux, Michel R., Scholey, Jonathan M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bardet-Biedl syndrome Biochemistry. Physiology. Immunology. Molecular biology Biological and medical sciences Biological Transport Caenorhabditis elegans - genetics Caenorhabditis elegans - physiology Caenorhabditis elegans Proteins - genetics Caenorhabditis elegans Proteins - metabolism Calcium-Binding Proteins - metabolism Care and treatment Cell physiology Cellular biology Cilia Cilia - genetics Cilia - physiology Development and progression Flagella - physiology Fundamental and applied biological sciences. Psychology Genes Genetic aspects Genetics Health aspects Humanities and Social Sciences Invertebrates Kinesin - metabolism letter Microscopy Molecular and cellular biology Molecular Motor Proteins - genetics Molecular Motor Proteins - physiology Motility and taxis multidisciplinary Muscle Proteins - metabolism Mutation Mutation - genetics Nemathelminthia. Plathelmintha Nerve Tissue Proteins - genetics Nerve Tissue Proteins - metabolism Physiology. Development Proteins Receptors, Cell Surface - genetics Receptors, Cell Surface - metabolism Science Time Factors Transport proteins
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