Comparison of Preference-Based Utilities of the 15D, EQ-5D and SF-6D in Patients with HIV/AIDS

Objective: This article compares preference-based utilities from the multiattribute utility instrument 15D with those derived from the EQ-5D and the Short Form 36 (SF-6D) in patients with HIV/AIDS. In particular, we wanted to examine if the finer descriptive system of the 15D would result in better...

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Veröffentlicht in:Quality of life research 2005-05, Vol.14 (4), p.971-980
Hauptverfasser: Stavem, Knut, Frøland, Stig S, Hellum, Kjell B
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Frøland, Stig S
Hellum, Kjell B
description Objective: This article compares preference-based utilities from the multiattribute utility instrument 15D with those derived from the EQ-5D and the Short Form 36 (SF-6D) in patients with HIV/AIDS. In particular, we wanted to examine if the finer descriptive system of the 15D would result in better discriminative capacity or responsiveness. Methods: In a prospective observational study of 60 Norwegian patients with HIV/AIDS from two hospitals, the authors compared scores, assessed associations with disease staging systems, and assessed test-retest reliability and responsiveness of the instruments. Results: On average, the 15D gave higher utility scores than the other two measures, the mean utility scores were: 15D - 0.86, SF-6D - 0.73, and EQ-5D Index - 0.77. Test-retest reliability was acceptable for all measures, with intraclass correlation coefficients between 0.78 and 0.94. The correlation between scores of the 3 scales was substantial (π = 0.74-0.80). There was no major difference in responsiveness between the measures. Conclusions: The different measures gave different utility values in this sample of patients with HIV/AIDS, although many of the measurement properties were similar. There was no evidence for better discriminative capacity or responsiveness for the 15D, than for the two other multiattribute measures.
doi_str_mv 10.1007/s11136-004-3211-7
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In particular, we wanted to examine if the finer descriptive system of the 15D would result in better discriminative capacity or responsiveness. Methods: In a prospective observational study of 60 Norwegian patients with HIV/AIDS from two hospitals, the authors compared scores, assessed associations with disease staging systems, and assessed test-retest reliability and responsiveness of the instruments. Results: On average, the 15D gave higher utility scores than the other two measures, the mean utility scores were: 15D - 0.86, SF-6D - 0.73, and EQ-5D Index - 0.77. Test-retest reliability was acceptable for all measures, with intraclass correlation coefficients between 0.78 and 0.94. The correlation between scores of the 3 scales was substantial (π = 0.74-0.80). There was no major difference in responsiveness between the measures. Conclusions: The different measures gave different utility values in this sample of patients with HIV/AIDS, although many of the measurement properties were similar. There was no evidence for better discriminative capacity or responsiveness for the 15D, than for the two other multiattribute measures.</description><identifier>ISSN: 0962-9343</identifier><identifier>EISSN: 1573-2649</identifier><identifier>DOI: 10.1007/s11136-004-3211-7</identifier><identifier>PMID: 16041894</identifier><language>eng</language><publisher>Netherlands: Springer</publisher><subject>Acquired immune deficiency syndrome ; Adult ; AIDS ; Diagnostic indices ; Epilepsy ; Female ; Health status ; Health surveys ; HIV ; HIV Seropositivity ; Human immunodeficiency virus ; Humans ; Male ; Middle Aged ; Norway ; Preference utilitarianism ; Preventive medicine ; Prospective Studies ; Quality of Life ; Reproducibility of Results ; Sickness Impact Profile ; Studies ; Surveys and Questionnaires ; Tariffs</subject><ispartof>Quality of life research, 2005-05, Vol.14 (4), p.971-980</ispartof><rights>Copyright 2005 Springer</rights><rights>Springer 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c378t-5226c8383e1dcddae5d100e6913746bb09c932a95378629194d838712b6246fd3</citedby><cites>FETCH-LOGICAL-c378t-5226c8383e1dcddae5d100e6913746bb09c932a95378629194d838712b6246fd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/4039360$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/4039360$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,776,780,799,27901,27902,57992,58225</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16041894$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stavem, Knut</creatorcontrib><creatorcontrib>Frøland, Stig S</creatorcontrib><creatorcontrib>Hellum, Kjell B</creatorcontrib><title>Comparison of Preference-Based Utilities of the 15D, EQ-5D and SF-6D in Patients with HIV/AIDS</title><title>Quality of life research</title><addtitle>Qual Life Res</addtitle><description>Objective: This article compares preference-based utilities from the multiattribute utility instrument 15D with those derived from the EQ-5D and the Short Form 36 (SF-6D) in patients with HIV/AIDS. In particular, we wanted to examine if the finer descriptive system of the 15D would result in better discriminative capacity or responsiveness. Methods: In a prospective observational study of 60 Norwegian patients with HIV/AIDS from two hospitals, the authors compared scores, assessed associations with disease staging systems, and assessed test-retest reliability and responsiveness of the instruments. Results: On average, the 15D gave higher utility scores than the other two measures, the mean utility scores were: 15D - 0.86, SF-6D - 0.73, and EQ-5D Index - 0.77. Test-retest reliability was acceptable for all measures, with intraclass correlation coefficients between 0.78 and 0.94. The correlation between scores of the 3 scales was substantial (π = 0.74-0.80). There was no major difference in responsiveness between the measures. 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In particular, we wanted to examine if the finer descriptive system of the 15D would result in better discriminative capacity or responsiveness. Methods: In a prospective observational study of 60 Norwegian patients with HIV/AIDS from two hospitals, the authors compared scores, assessed associations with disease staging systems, and assessed test-retest reliability and responsiveness of the instruments. Results: On average, the 15D gave higher utility scores than the other two measures, the mean utility scores were: 15D - 0.86, SF-6D - 0.73, and EQ-5D Index - 0.77. Test-retest reliability was acceptable for all measures, with intraclass correlation coefficients between 0.78 and 0.94. The correlation between scores of the 3 scales was substantial (π = 0.74-0.80). There was no major difference in responsiveness between the measures. Conclusions: The different measures gave different utility values in this sample of patients with HIV/AIDS, although many of the measurement properties were similar. There was no evidence for better discriminative capacity or responsiveness for the 15D, than for the two other multiattribute measures.</abstract><cop>Netherlands</cop><pub>Springer</pub><pmid>16041894</pmid><doi>10.1007/s11136-004-3211-7</doi><tpages>10</tpages></addata></record>
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subjects Acquired immune deficiency syndrome
Adult
AIDS
Diagnostic indices
Epilepsy
Female
Health status
Health surveys
HIV
HIV Seropositivity
Human immunodeficiency virus
Humans
Male
Middle Aged
Norway
Preference utilitarianism
Preventive medicine
Prospective Studies
Quality of Life
Reproducibility of Results
Sickness Impact Profile
Studies
Surveys and Questionnaires
Tariffs
title Comparison of Preference-Based Utilities of the 15D, EQ-5D and SF-6D in Patients with HIV/AIDS
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