Mitochondrial membrane potential and reactive oxygen species content of endothelial and smooth muscle cells cultured on poly( ε-caprolactone) films

A transitory but significant stimulation of mitochondrial activity, increase of reactive oxygen species (ROS) and oxidative stress were previously observed in L929 fibroblasts cultured on poly( ε-caprolactone) (PCL) films. ROS, mainly formed in mitochondria, play a physiological role but an excessiv...

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Veröffentlicht in:	Biomaterials 2006-09, Vol.27 (27), p.4706-4714
Hauptverfasser:	Serrano, M. Concepción, Pagani, Raffaella, Manzano, Miguel, Comas, Juan V., Portolés, M. Teresa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biocompatibility Biocompatible Materials - chemistry Cell Adhesion Cell Culture Techniques - methods Cell Survival Cells, Cultured Endothelial cells Endothelial Cells - physiology Endothelial Cells - ultrastructure Materials Testing Membrane Potentials - physiology Membranes, Artificial Mitochondrial membrane potential Mitochondrial Membranes - physiology Mitochondrial Membranes - ultrastructure Myocytes, Smooth Muscle - physiology Myocytes, Smooth Muscle - ultrastructure Polycaprolactone Polyesters - chemistry Reactive oxygen species Reactive Oxygen Species - metabolism Smooth muscle cells Swine Tissue Engineering - methods
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