Mycobacterium tuberculosis Regulates CD1 Antigen Presentation Pathways through TLR-2

Mycobacterium tuberculosis remains a major pathogen of worldwide importance, which releases lipid Ags that are presented to human T cells during the course of tuberculosis infections. Here we report that cellular infection with live M. tuberculosis or exposure to mycobacterial cell wall products con...

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Veröffentlicht in:	The Journal of immunology (1950) 2005-08, Vol.175 (3), p.1758-1766
Hauptverfasser:	Roura-Mir, Carme, Wang, Lisheng, Cheng, Tan-Yun, Matsunaga, Isamu, Dascher, Christopher C, Peng, Stanford L, Fenton, Matthew J, Kirschning, Carsten, Moody, D. Branch
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen Presentation - immunology Antigens, CD1 - biosynthesis Antigens, CD1 - immunology Antigens, CD1 - metabolism Cell Line Cell Wall - chemistry Cell Wall - immunology CHO Cells Cricetinae Galactans - immunology Glycoproteins Humans Lipopolysaccharides - immunology Membrane Glycoproteins - agonists Membrane Glycoproteins - physiology Monocytes - immunology Monocytes - metabolism Mycobacterium tuberculosis - chemistry Mycobacterium tuberculosis - immunology Oxazoles - immunology Peptidoglycan - immunology Protein Biosynthesis - immunology Receptors, Cell Surface - agonists Receptors, Cell Surface - physiology Signal Transduction - immunology Toll-Like Receptor 2 Toll-Like Receptors
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