A 10-year review of the occurrence and treatment of central giant cell granulomas, in a District General Hospital
Background: There is considerable variation in the clinical presentation, behaviour and radiological appearance of central giant cell granulomas (CGCGs), for which multiple treatment modalities have been suggested. Method: A 10‐year retrospective review of the clinical presentation, radiological f...
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| Veröffentlicht in: | Journal of oral pathology & medicine 2006-07, Vol.35 (6), p.332-337 |
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| container_title | Journal of oral pathology & medicine |
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| creator | Farrier, S. L. Farrier, J. N. Smart, M. K. Nash, E. S. |
| description | Background: There is considerable variation in the clinical presentation, behaviour and radiological appearance of central giant cell granulomas (CGCGs), for which multiple treatment modalities have been suggested.
Method: A 10‐year retrospective review of the clinical presentation, radiological features and treatment received was undertaken.
Results: The cohort of patients included six males and three females, with an age range of 7–61 years. Six lesions were in the mandible and three in the maxilla. Eight lesions presented with swelling, three in relation to teeth. One case was an incidental finding. Six cases were confined within the cortical plates, one involved soft tissue. Radiological presentation was diverse, but within the existing confines of CGCGs. With one exception, primary treatment was surgical resection with excisional curettage of the remaining bone; to date, none have recurred.
Conclusion: Diagnosis relies on correct interpretation of clinical, radiographical and histopathological data. Alternative treatments are worthy of consideration, although surgical excision remains the treatment of choice. |
| doi_str_mv | 10.1111/j.1600-0714.2006.00384.x |
| format | Article |
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Method: A 10‐year retrospective review of the clinical presentation, radiological features and treatment received was undertaken.
Results: The cohort of patients included six males and three females, with an age range of 7–61 years. Six lesions were in the mandible and three in the maxilla. Eight lesions presented with swelling, three in relation to teeth. One case was an incidental finding. Six cases were confined within the cortical plates, one involved soft tissue. Radiological presentation was diverse, but within the existing confines of CGCGs. With one exception, primary treatment was surgical resection with excisional curettage of the remaining bone; to date, none have recurred.
Conclusion: Diagnosis relies on correct interpretation of clinical, radiographical and histopathological data. Alternative treatments are worthy of consideration, although surgical excision remains the treatment of choice.</description><identifier>ISSN: 0904-2512</identifier><identifier>EISSN: 1600-0714</identifier><identifier>DOI: 10.1111/j.1600-0714.2006.00384.x</identifier><identifier>PMID: 16762013</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adolescent ; Adult ; calcitonin ; Child ; corticosteroid ; Dentistry ; diagnosis ; Female ; giant cell ; granuloma ; Granuloma, Giant Cell - diagnostic imaging ; Granuloma, Giant Cell - pathology ; Granuloma, Giant Cell - surgery ; Hospitals, District ; Humans ; Jaw Diseases - diagnostic imaging ; Jaw Diseases - pathology ; Jaw Diseases - surgery ; Male ; Middle Aged ; oral ; outcome ; Radiography ; Retrospective Studies ; treatment</subject><ispartof>Journal of oral pathology & medicine, 2006-07, Vol.35 (6), p.332-337</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4704-3abe7a7c6b9f23e165bcfa7e2f65b0fe4a29d889a1a7a3d2853a53bcfeb9ccd33</citedby><cites>FETCH-LOGICAL-c4704-3abe7a7c6b9f23e165bcfa7e2f65b0fe4a29d889a1a7a3d2853a53bcfeb9ccd33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1600-0714.2006.00384.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1600-0714.2006.00384.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16762013$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Farrier, S. L.</creatorcontrib><creatorcontrib>Farrier, J. N.</creatorcontrib><creatorcontrib>Smart, M. K.</creatorcontrib><creatorcontrib>Nash, E. S.</creatorcontrib><title>A 10-year review of the occurrence and treatment of central giant cell granulomas, in a District General Hospital</title><title>Journal of oral pathology & medicine</title><addtitle>J Oral Pathol Med</addtitle><description>Background: There is considerable variation in the clinical presentation, behaviour and radiological appearance of central giant cell granulomas (CGCGs), for which multiple treatment modalities have been suggested.
Method: A 10‐year retrospective review of the clinical presentation, radiological features and treatment received was undertaken.
Results: The cohort of patients included six males and three females, with an age range of 7–61 years. Six lesions were in the mandible and three in the maxilla. Eight lesions presented with swelling, three in relation to teeth. One case was an incidental finding. Six cases were confined within the cortical plates, one involved soft tissue. Radiological presentation was diverse, but within the existing confines of CGCGs. With one exception, primary treatment was surgical resection with excisional curettage of the remaining bone; to date, none have recurred.
Conclusion: Diagnosis relies on correct interpretation of clinical, radiographical and histopathological data. Alternative treatments are worthy of consideration, although surgical excision remains the treatment of choice.</description><subject>Adolescent</subject><subject>Adult</subject><subject>calcitonin</subject><subject>Child</subject><subject>corticosteroid</subject><subject>Dentistry</subject><subject>diagnosis</subject><subject>Female</subject><subject>giant cell</subject><subject>granuloma</subject><subject>Granuloma, Giant Cell - diagnostic imaging</subject><subject>Granuloma, Giant Cell - pathology</subject><subject>Granuloma, Giant Cell - surgery</subject><subject>Hospitals, District</subject><subject>Humans</subject><subject>Jaw Diseases - diagnostic imaging</subject><subject>Jaw Diseases - pathology</subject><subject>Jaw Diseases - surgery</subject><subject>Male</subject><subject>Middle Aged</subject><subject>oral</subject><subject>outcome</subject><subject>Radiography</subject><subject>Retrospective Studies</subject><subject>treatment</subject><issn>0904-2512</issn><issn>1600-0714</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkElv2zAQhYmiReMsf6HgqadK5SKJEtBL4DZOiixF1t6IETVq6WpxSCmx_32p2Eiv5WUGnPfeDD5CKGcxD-_zMuYZYxFTPIkFY1nMmMyTeP2GzF4Hb8mMFSyJRMrFHtn3fskYVzLh78kez1QmGJcz8ngcQqMNgqMOnyw-076mw2-kvTGjc9gZpNBVdHAIQ4vdMM1NqA4a-stC-DDYhNZBNzZ9C_4TtR0F-tX6wVkz0AV2OIlPe7-yAzSH5F0NjcejXT0gdyffbuen0fnV4mx-fB6ZRIWzJZSoQJmsLGohkWdpaWpQKOrQsRoTEEWV5wVwUCArkacSUhk0WBbGVFIekI_b3JXrH0f0g26tn26FDvvR6yxnaSHyIgjzrdC43nuHtV4524LbaM70hFsv9URVT1T1hFu_4NbrYP2w2zGWLVb_jDu-QfBlK3i2DW7-O1h_v_oRmmCPtvYAE9evdnB_dKakSvXD5ULfz28efsr5hb6WfwFB6J6N</recordid><startdate>200607</startdate><enddate>200607</enddate><creator>Farrier, S. L.</creator><creator>Farrier, J. N.</creator><creator>Smart, M. K.</creator><creator>Nash, E. S.</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200607</creationdate><title>A 10-year review of the occurrence and treatment of central giant cell granulomas, in a District General Hospital</title><author>Farrier, S. L. ; Farrier, J. N. ; Smart, M. K. ; Nash, E. S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4704-3abe7a7c6b9f23e165bcfa7e2f65b0fe4a29d889a1a7a3d2853a53bcfeb9ccd33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>calcitonin</topic><topic>Child</topic><topic>corticosteroid</topic><topic>Dentistry</topic><topic>diagnosis</topic><topic>Female</topic><topic>giant cell</topic><topic>granuloma</topic><topic>Granuloma, Giant Cell - diagnostic imaging</topic><topic>Granuloma, Giant Cell - pathology</topic><topic>Granuloma, Giant Cell - surgery</topic><topic>Hospitals, District</topic><topic>Humans</topic><topic>Jaw Diseases - diagnostic imaging</topic><topic>Jaw Diseases - pathology</topic><topic>Jaw Diseases - surgery</topic><topic>Male</topic><topic>Middle Aged</topic><topic>oral</topic><topic>outcome</topic><topic>Radiography</topic><topic>Retrospective Studies</topic><topic>treatment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Farrier, S. L.</creatorcontrib><creatorcontrib>Farrier, J. N.</creatorcontrib><creatorcontrib>Smart, M. K.</creatorcontrib><creatorcontrib>Nash, E. S.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of oral pathology & medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Farrier, S. L.</au><au>Farrier, J. N.</au><au>Smart, M. K.</au><au>Nash, E. S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A 10-year review of the occurrence and treatment of central giant cell granulomas, in a District General Hospital</atitle><jtitle>Journal of oral pathology & medicine</jtitle><addtitle>J Oral Pathol Med</addtitle><date>2006-07</date><risdate>2006</risdate><volume>35</volume><issue>6</issue><spage>332</spage><epage>337</epage><pages>332-337</pages><issn>0904-2512</issn><eissn>1600-0714</eissn><abstract>Background: There is considerable variation in the clinical presentation, behaviour and radiological appearance of central giant cell granulomas (CGCGs), for which multiple treatment modalities have been suggested.
Method: A 10‐year retrospective review of the clinical presentation, radiological features and treatment received was undertaken.
Results: The cohort of patients included six males and three females, with an age range of 7–61 years. Six lesions were in the mandible and three in the maxilla. Eight lesions presented with swelling, three in relation to teeth. One case was an incidental finding. Six cases were confined within the cortical plates, one involved soft tissue. Radiological presentation was diverse, but within the existing confines of CGCGs. With one exception, primary treatment was surgical resection with excisional curettage of the remaining bone; to date, none have recurred.
Conclusion: Diagnosis relies on correct interpretation of clinical, radiographical and histopathological data. Alternative treatments are worthy of consideration, although surgical excision remains the treatment of choice.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>16762013</pmid><doi>10.1111/j.1600-0714.2006.00384.x</doi><tpages>6</tpages></addata></record> |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adolescent Adult calcitonin Child corticosteroid Dentistry diagnosis Female giant cell granuloma Granuloma, Giant Cell - diagnostic imaging Granuloma, Giant Cell - pathology Granuloma, Giant Cell - surgery Hospitals, District Humans Jaw Diseases - diagnostic imaging Jaw Diseases - pathology Jaw Diseases - surgery Male Middle Aged oral outcome Radiography Retrospective Studies treatment |
| title | A 10-year review of the occurrence and treatment of central giant cell granulomas, in a District General Hospital |
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