Characterization of β-Hydroxy-β-methylglutaryl Coenzyme A Reductase Inhibitor from Pueraria thunbergiana

This study describes the extraction and characterization of an inhibitor for β-hydroxy-β-methylglutaryl (HMG) coenzyme A (CoA) reductase from Pueraria thunbergiana. The maximum HMG-CoA reductase inhibitory activity (IC50 = 79 μg) was obtained when P. thunbergiana was extracted with 70% ethanol at 30...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2005-07, Vol.53 (15), p.5882-5888
Hauptverfasser:	Kim, Hyoung-Jong, Lee, Dae-Hyoung, Hwang, Yoo-Yeon, Lee, Ki-Sung, Lee, Jong-Soo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antilipemic agents Biological and medical sciences Cercopithecus aethiops Cricetinae daidzein enzyme inhibition enzyme inhibitors Food industries Fundamental and applied biological sciences. Psychology Hydroxymethylglutaryl CoA Reductases - metabolism hydroxymethylglutaryl-CoA lyase Hydroxymethylglutaryl-CoA Reductase Inhibitors - isolation & purification Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology Hypolipidemic Agents - pharmacology medicinal plants Mesocricetus plant extracts Pueraria - chemistry Pueraria montana var. lobata Vero Cells
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