KiSS-1 and GPR54 as new players in gonadotropin regulation and puberty

The recent identification of loss-of-function mutations in the gene encoding GPR54, the receptor for the KiSS-1-derived peptides, kisspeptins, has highlighted a previously unrecognized pathway in the physiologic regulation of puberty and reproduction. Patients with loss-of-function mutations in GPR5...

Ausführliche Beschreibung