Randomized, Controlled Study of the Safety and Immunogenicity of Peru-15, a Live Attenuated Oral Vaccine Candidate for Cholera, in Adult Volunteers in Bangladesh

BackgroundA live oral Vibrio cholerae O1 El Tor vaccine candidate, Peru-15, was studied for safety, immunogenicity, and excretion in phase 1 (inpatient) and phase 2 (outpatient) studies of Bangladeshi adults MethodsThe study was conducted among adults, by use of a double-blind, randomized, placebo-c...

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Veröffentlicht in:	The Journal of infectious diseases 2005-08, Vol.192 (4), p.573-579
Hauptverfasser:	Qadri, Firdausi, Chowdhury, Mohiul I., Faruque, Shah M., Salam, Mohammed A., Ahmed, Tanvir, Begum, Yasmin A., Saha, Amit, Alam, Mohammed S., Zaman, K., Seidlein, Lorenz V., Park, Eunsik, Killeen, Kevin P., Mekalanos, John J., Clemens, John D., Sack, David A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Antibodies Antibodies, Bacterial - blood Applied microbiology Bacteria Bacterial diseases Bacteriology Bangladesh Biological and medical sciences Cholera Cholera vaccine Cholera Vaccines - adverse effects Cholera Vaccines - immunology Female Fundamental and applied biological sciences. Psychology Human bacterial diseases Humans Immune response Immunization Immunoglobulin G - blood Immunoglobulin M - blood Infectious diseases Isotypes Male Medical sciences Microbiology Middle Aged Miscellaneous Placebos Transponders Tropical bacterial diseases Vaccination Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vaccines, Attenuated - adverse effects Vaccines, Attenuated - immunology Vibrio cholerae Vibrio cholerae - immunology
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