Hypermethylation of CpG islands in p16 as a prognostic factor for diffuse large B-cell lymphoma in a high-risk group

The aim of the study was to analyze the methylation status of the promoter regions of p15 and p16 and to assess the prognostic significance of promoter hypermethylation in diffuse large B-cell lymphoma (DLBCL). DLBCL was diagnosed by morphology and immunohistochemical analysis according to the World...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Leukemia research 2006-07, Vol.30 (7), p.859-867
Hauptverfasser:	Shiozawa, Eisuke, Takimoto, Masafumi, Makino, Reiko, Adachi, Daisuke, Saito, Bungo, Yamochi-Onizuka, Toshiko, Yamochi, Tadanori, Shimozuma, Junko, Maeda, Takashi, Kohno, Yohko, Kawakami, Keiichiro, Nakamaki, Tsuyoshi, Tomoyasu, Shigeru, Shiokawa, Akira, Ota, Hidekazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomarkers, Tumor - genetics CpG Islands Cyclin-Dependent Kinase Inhibitor p15 - genetics Cyclin-Dependent Kinase Inhibitor p16 - genetics Diffuse large B-cell lymphoma DNA Methylation Female Humans International prognostic index (IPI) Lymphoma, B-Cell - diagnosis Lymphoma, B-Cell - genetics Lymphoma, Large B-Cell, Diffuse - diagnosis Lymphoma, Large B-Cell, Diffuse - genetics Male Methylation Middle Aged Multivariate Analysis Neoplasm Staging p16 Predictive Value of Tests Prognosis Risk Factors Survival Rate Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!