Chemical tools for activity-based proteomics

Chemical tools for activity-based proteomics

Several approaches for proteome analysis and the generation of proteome subsets rely on engineered chemical probes that are tailored towards the detection of different protein classes. The concepts are presented in this review covering the literature until mid-2005.

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Bibliographische Detailangaben
Veröffentlicht in:Journal of biotechnology 2006-06, Vol.124 (1), p.56-73
Hauptverfasser: Hagenstein, Miriam C., Sewald, Norbert
Format: Artikel
Sprache:eng
Schlagworte:
Activity-based profiling
Chemical probes
Enzyme Inhibitors - chemistry
Enzyme Inhibitors - metabolism
Forecasting
Gene Expression Profiling
Inhibitors
Ligands
Molecular Probes
Molecular Structure
Protein ligands
Proteins - chemistry
Proteins - genetics
Proteins - metabolism
Proteomics - methods
Proteomics techniques
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Beschreibung
Zusammenfassung:Several approaches for proteome analysis and the generation of proteome subsets rely on engineered chemical probes that are tailored towards the detection of different protein classes. The concepts are presented in this review covering the literature until mid-2005.
ISSN:0168-1656
1873-4863
DOI:10.1016/j.jbiotec.2005.12.005