EphB2 induces proliferation and promotes a neuronal fate in adult subventricular neural precursor cells

The subventricular germinal zone (SVZ) retains an active population of stem cells and neural precursor cells throughout adulthood. EphrinB signaling mediates angiogenesis and vasculogenesis in the developing and adult brain. Recent studies indicate that molecules involved in angiogenesis often influ...

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Veröffentlicht in:	Neuroscience letters 2005-09, Vol.385 (3), p.204-209
Hauptverfasser:	Katakowski, Mark, Zhang, Zhenggang, deCarvalho, Ana C., Chopp, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Differentiation - physiology Cell Movement Cell Proliferation Cells, Cultured EphB2 Ephrin Fundamental and applied biological sciences. Psychology Immunohistochemistry Lateral Ventricles - cytology Male Mice Microspheres Neural precursors Neurogenesis Neurons - cytology Neurons - metabolism Notch1 Receptor, EphB2 - metabolism Receptor, Notch1 Receptors, Cell Surface - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis Stem Cells - cytology Stem Cells - metabolism Subventricular zone Transcription Factors - metabolism Vertebrates: nervous system and sense organs
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