Pentacyclic Triterpenoids from Leaves of Excoecaria agallocha
A new oleanane-type triterpenoid (1) and five known pentacyclic triterpenoids (2—6) were isolated from the leaves of Excoecaria agallocha. Their structures were elucidated by spectroscopic analyses. The new compound was characterized as 3β-[(2E,4E)-5-oxo-decadienoyloxy]-olean-12-ene (1). Compounds 1...
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| Veröffentlicht in: | Chemical & Pharmaceutical Bulletin 2006, Vol.54(6), pp.920-921 |
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| container_title | Chemical & Pharmaceutical Bulletin |
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| creator | Zou, Jian-Hua Dai, Jungui Chen, Xiaoguang Yuan, Jing-Quan |
| description | A new oleanane-type triterpenoid (1) and five known pentacyclic triterpenoids (2—6) were isolated from the leaves of Excoecaria agallocha. Their structures were elucidated by spectroscopic analyses. The new compound was characterized as 3β-[(2E,4E)-5-oxo-decadienoyloxy]-olean-12-ene (1). Compounds 1—6 were found inactive in vitro against several human cancer cell lines. |
| doi_str_mv | 10.1248/cpb.54.920 |
| format | Article |
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Their structures were elucidated by spectroscopic analyses. The new compound was characterized as 3β-[(2E,4E)-5-oxo-decadienoyloxy]-olean-12-ene (1). 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Pharm. Bull.</addtitle><description>A new oleanane-type triterpenoid (1) and five known pentacyclic triterpenoids (2—6) were isolated from the leaves of Excoecaria agallocha. Their structures were elucidated by spectroscopic analyses. The new compound was characterized as 3β-[(2E,4E)-5-oxo-decadienoyloxy]-olean-12-ene (1). Compounds 1—6 were found inactive in vitro against several human cancer cell lines.</description><subject>Caco-2 Cells</subject><subject>Euphorbiaceae - chemistry</subject><subject>Excoecaria agallocha</subject><subject>Humans</subject><subject>mangrove</subject><subject>Oleanolic Acid - analogs & derivatives</subject><subject>Oleanolic Acid - isolation & purification</subject><subject>Oleanolic Acid - pharmacology</subject><subject>Pentacyclic Triterpenes - isolation & purification</subject><subject>Pentacyclic Triterpenes - pharmacology</subject><subject>pentacyclic triterpenoid</subject><subject>Plant Leaves - chemistry</subject><issn>0009-2363</issn><issn>1347-5223</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkE2LFDEQhoMo7rh68QdIg-BB6LHy3X0QkWVdhQE9rOeQTlfvZEh3xqRH3H9vmh53wUtVoJ48VbyEvKawpUw0H9yx20qxbRk8IRvKha4lY_wp2QBAWzOu-AV5kfMBgEnQ_Dm5oErL5bkhH3_gNFt374J31W3yM6YjTtH3uRpSHKsd2t-YqzhU139cRGeTt5W9syFEt7cvybPBhoyvzv2S_PxyfXv1td59v_l29XlXO6Vgrlnb0F4o2jmnoENJ-17Lnnc46E62HdcdbVvdUoaDHHrX84E5pa0SDihYyfklebd6jyn-OmGezeizwxDshPGUjWpACCabAr79DzzEU5rKbYYKBbzRQrWFer9SLsWcEw7mmPxo072hYJZITYnUSGFKpAV-c1aeuhH7R_ScYQFuVqBMvbMhTsFP-LjYZe32OHrDAJQBkGJpnBso-qVQCpoqpYrp02o65Nne4cMqm2bvAv67Sq1l-f0w2dtkcOJ_AeZHna8</recordid><startdate>20060601</startdate><enddate>20060601</enddate><creator>Zou, Jian-Hua</creator><creator>Dai, Jungui</creator><creator>Chen, Xiaoguang</creator><creator>Yuan, Jing-Quan</creator><general>The Pharmaceutical Society of Japan</general><general>Pharmaceutical Society of Japan</general><general>Japan Science and Technology Agency</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7TM</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>20060601</creationdate><title>Pentacyclic Triterpenoids from Leaves of Excoecaria agallocha</title><author>Zou, Jian-Hua ; Dai, Jungui ; Chen, Xiaoguang ; Yuan, Jing-Quan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c660t-2981d461bcc60be51dd75d3bef7b59b37b1997912ef5fdcd3f2c67a64c010a533</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Caco-2 Cells</topic><topic>Euphorbiaceae - chemistry</topic><topic>Excoecaria agallocha</topic><topic>Humans</topic><topic>mangrove</topic><topic>Oleanolic Acid - analogs & derivatives</topic><topic>Oleanolic Acid - isolation & purification</topic><topic>Oleanolic Acid - pharmacology</topic><topic>Pentacyclic Triterpenes - isolation & purification</topic><topic>Pentacyclic Triterpenes - pharmacology</topic><topic>pentacyclic triterpenoid</topic><topic>Plant Leaves - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zou, Jian-Hua</creatorcontrib><creatorcontrib>Dai, Jungui</creatorcontrib><creatorcontrib>Chen, Xiaoguang</creatorcontrib><creatorcontrib>Yuan, Jing-Quan</creatorcontrib><creatorcontrib>Ministry of Education</creatorcontrib><creatorcontrib>Chinese Academy of Medical Sciences and Peking Union Medical College</creatorcontrib><creatorcontrib>cGuangxi Affiliated Institute of Medicinal Plant Development</creatorcontrib><creatorcontrib>aKey Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Peking Union Medical College</creatorcontrib><creatorcontrib>binstitute of Materia Medica</creatorcontrib><creatorcontrib>Chinese Academy of Medical Sciences & Guangxi Institute of Medicinal Plant</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Chemical & Pharmaceutical Bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zou, Jian-Hua</au><au>Dai, Jungui</au><au>Chen, Xiaoguang</au><au>Yuan, Jing-Quan</au><aucorp>Ministry of Education</aucorp><aucorp>Chinese Academy of Medical Sciences and Peking Union Medical College</aucorp><aucorp>cGuangxi Affiliated Institute of Medicinal Plant Development</aucorp><aucorp>aKey Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine (Peking Union Medical College</aucorp><aucorp>binstitute of Materia Medica</aucorp><aucorp>Chinese Academy of Medical Sciences & Guangxi Institute of Medicinal Plant</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pentacyclic Triterpenoids from Leaves of Excoecaria agallocha</atitle><jtitle>Chemical & Pharmaceutical Bulletin</jtitle><addtitle>Chem. 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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; Free Full-Text Journals in Chemistry |
| subjects | Caco-2 Cells Euphorbiaceae - chemistry Excoecaria agallocha Humans mangrove Oleanolic Acid - analogs & derivatives Oleanolic Acid - isolation & purification Oleanolic Acid - pharmacology Pentacyclic Triterpenes - isolation & purification Pentacyclic Triterpenes - pharmacology pentacyclic triterpenoid Plant Leaves - chemistry |
| title | Pentacyclic Triterpenoids from Leaves of Excoecaria agallocha |
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