The Effects of Debanding on the Lung Expression of ET-1, eNOS, and cGMP in Rats with Left Ventricular Pressure Overload

Pulmonary hypertension (PH) usually develops secondary to left ventricular (LV) dysfunction; therefore, it is also called retrograde PH. To investigate our hypothesis that PH is at least partially reversible, as in some congenital heart diseases, in a rat model we investigated whether release of con...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 2006-06, Vol.231 (6), p.954-959
Hauptverfasser:	Chou, Shah-Hwa, Chai, Chee-Yin, Wu, Jiunn-Ren, Tan, Mian-Shin, Chiu, Chaw-Chi, Chen, Ing-Jun, Jeng, Acro Y., Chang, Chung-I, Kwan, Aij-Lie, Dai, Zen-Kong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cyclic GMP - metabolism Disease Models, Animal Endothelin-1 - metabolism Hypertension, Pulmonary - metabolism Hypertension, Pulmonary - pathology Lung - metabolism Lung - pathology Male Nitric Oxide Synthase Type III - metabolism Rats Rats, Wistar Ventricular Dysfunction, Left - enzymology Ventricular Dysfunction, Left - metabolism Ventricular Dysfunction, Left - pathology
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