Strategies to eliminate cancer stem cells: Clinical implications

Over the past two decades, major advances in our understanding of cancer have translated into only modest increments in survival for the majority of cancer patients. Recent data suggesting cancers arise from rare self-renewing stem cells that are biologically distinct from their more numerous differ...

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Veröffentlicht in:	European journal of cancer (1990) 2006-06, Vol.42 (9), p.1293-1297
Hauptverfasser:	Huff, Carol Ann, Matsui, William H., Douglas Smith, B., Jones, Richard J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - therapeutic use Benzamides Cancer stem cells Cell Differentiation Chronic myeloid leukaemia Drug Design Drug resistance Drug Resistance, Neoplasm Humans Imatinib Imatinib Mesylate Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology Neoplastic Stem Cells - drug effects Piperazines - therapeutic use Pyrimidines - therapeutic use Stem cells Therapeutics
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