Muscle hypertrophy with complex repetitive discharges in C-6 radiculopathy

Objective: To report on a case of post-denervation muscle hypertrophy in an unusual distribution. Case report: A 52-year-old patient with severe flaccid paraparesis after polio developed unilateral C-6 radiculopathy that resolved with conservative treatment. Within 2 years marked hypertrophy, stiffn...

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Veröffentlicht in:Clinical neurology and neurosurgery 2005-08, Vol.107 (5), p.425-427
Hauptverfasser: Rousseff, Rossen T., Tzvetanov, Plamen
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creator Rousseff, Rossen T.
Tzvetanov, Plamen
description Objective: To report on a case of post-denervation muscle hypertrophy in an unusual distribution. Case report: A 52-year-old patient with severe flaccid paraparesis after polio developed unilateral C-6 radiculopathy that resolved with conservative treatment. Within 2 years marked hypertrophy, stiffness and pain in the muscles in the affected myotome developed. EMG discovered abundant complex repetitive discharges (CRD) within hypertrophic muscles. On biopsy, true hypertrophy of muscle fibers and some group atrophy was found. Steroid treatment relieved the symptoms and significantly suppressed the CRD. The possible causative role of CRD for hypertrophy in partially denervated muscle is discussed.
doi_str_mv 10.1016/j.clineuro.2004.09.019
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subjects Biological and medical sciences
Complex repetitive discharges
Humans
Hypertrophy - etiology
Hypertrophy - pathology
Hypertrophy - physiopathology
Male
Medical sciences
Middle Aged
Muscle hypertrophy
Muscle, Skeletal - pathology
Muscle, Skeletal - physiopathology
Neurology
Neurosurgery
Radiculopathy
Radiculopathy - complications
Radiculopathy - pathology
Radiculopathy - physiopathology
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
title Muscle hypertrophy with complex repetitive discharges in C-6 radiculopathy
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