Muscle hypertrophy with complex repetitive discharges in C-6 radiculopathy
Objective: To report on a case of post-denervation muscle hypertrophy in an unusual distribution. Case report: A 52-year-old patient with severe flaccid paraparesis after polio developed unilateral C-6 radiculopathy that resolved with conservative treatment. Within 2 years marked hypertrophy, stiffn...
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Veröffentlicht in: | Clinical neurology and neurosurgery 2005-08, Vol.107 (5), p.425-427 |
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description | Objective: To report on a case of post-denervation muscle hypertrophy in an unusual distribution. Case report: A 52-year-old patient with severe flaccid paraparesis after polio developed unilateral C-6 radiculopathy that resolved with conservative treatment. Within 2 years marked hypertrophy, stiffness and pain in the muscles in the affected myotome developed. EMG discovered abundant complex repetitive discharges (CRD) within hypertrophic muscles. On biopsy, true hypertrophy of muscle fibers and some group atrophy was found. Steroid treatment relieved the symptoms and significantly suppressed the CRD. The possible causative role of CRD for hypertrophy in partially denervated muscle is discussed. |
doi_str_mv | 10.1016/j.clineuro.2004.09.019 |
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Case report: A 52-year-old patient with severe flaccid paraparesis after polio developed unilateral C-6 radiculopathy that resolved with conservative treatment. Within 2 years marked hypertrophy, stiffness and pain in the muscles in the affected myotome developed. EMG discovered abundant complex repetitive discharges (CRD) within hypertrophic muscles. On biopsy, true hypertrophy of muscle fibers and some group atrophy was found. Steroid treatment relieved the symptoms and significantly suppressed the CRD. The possible causative role of CRD for hypertrophy in partially denervated muscle is discussed.</description><identifier>ISSN: 0303-8467</identifier><identifier>EISSN: 1872-6968</identifier><identifier>DOI: 10.1016/j.clineuro.2004.09.019</identifier><identifier>PMID: 16023540</identifier><identifier>CODEN: CNNSBV</identifier><language>eng</language><publisher>Amsterdam: Elsevier B.V</publisher><subject>Biological and medical sciences ; Complex repetitive discharges ; Humans ; Hypertrophy - etiology ; Hypertrophy - pathology ; Hypertrophy - physiopathology ; Male ; Medical sciences ; Middle Aged ; Muscle hypertrophy ; Muscle, Skeletal - pathology ; Muscle, Skeletal - physiopathology ; Neurology ; Neurosurgery ; Radiculopathy ; Radiculopathy - complications ; Radiculopathy - pathology ; Radiculopathy - physiopathology ; Surgery (general aspects). Transplantations, organ and tissue grafts. 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Case report: A 52-year-old patient with severe flaccid paraparesis after polio developed unilateral C-6 radiculopathy that resolved with conservative treatment. Within 2 years marked hypertrophy, stiffness and pain in the muscles in the affected myotome developed. EMG discovered abundant complex repetitive discharges (CRD) within hypertrophic muscles. On biopsy, true hypertrophy of muscle fibers and some group atrophy was found. Steroid treatment relieved the symptoms and significantly suppressed the CRD. The possible causative role of CRD for hypertrophy in partially denervated muscle is discussed.</description><subject>Biological and medical sciences</subject><subject>Complex repetitive discharges</subject><subject>Humans</subject><subject>Hypertrophy - etiology</subject><subject>Hypertrophy - pathology</subject><subject>Hypertrophy - physiopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Muscle hypertrophy</subject><subject>Muscle, Skeletal - pathology</subject><subject>Muscle, Skeletal - physiopathology</subject><subject>Neurology</subject><subject>Neurosurgery</subject><subject>Radiculopathy</subject><subject>Radiculopathy - complications</subject><subject>Radiculopathy - pathology</subject><subject>Radiculopathy - physiopathology</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. 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Transplantations, organ and tissue grafts. 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subjects | Biological and medical sciences Complex repetitive discharges Humans Hypertrophy - etiology Hypertrophy - pathology Hypertrophy - physiopathology Male Medical sciences Middle Aged Muscle hypertrophy Muscle, Skeletal - pathology Muscle, Skeletal - physiopathology Neurology Neurosurgery Radiculopathy Radiculopathy - complications Radiculopathy - pathology Radiculopathy - physiopathology Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases |
title | Muscle hypertrophy with complex repetitive discharges in C-6 radiculopathy |
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