Myelin-associated Glycoprotein Inhibits Microtubule Assembly by a Rho-kinase-dependent Mechanism

Myelin-associated glycoprotein (MAG) and Nogo are potent inhibitors of neurite outgrowth from a variety of neurons, and they have been identified as possible components of the central nervous system myelin that prevents axonal regeneration in the adult vertebrate central nervous system. The activati...

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Veröffentlicht in:	The Journal of biological chemistry 2006-06, Vol.281 (23), p.15970-15979
Hauptverfasser:	Mimura, Fumiaki, Yamagishi, Satoru, Arimura, Nariko, Fujitani, Masashi, Kubo, Takekazu, Kaibuchi, Kozo, Yamashita, Toshihide
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Blotting, Western DNA Primers Fluorescent Antibody Technique Intercellular Signaling Peptides and Proteins Microtubules - physiology Myelin Proteins - physiology Myelin-Associated Glycoprotein - physiology Nerve Tissue Proteins - physiology Nogo Proteins Phosphorylation Rats rho GTP-Binding Proteins - physiology
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