Human Histological Research: Is It Necessary? Humane? Ethical?

A review of the dental literature in the United States over the past 60 years is replete with studies utilizing human histological evidence for research. The first reference found for the use of human tissue for histological study was published in 1941 in the Journal of Dental Research.1 Much of thi...

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Veröffentlicht in:Journal of periodontology (1970) 2005-07, Vol.76 (7), p.1207-1210
Hauptverfasser: Leib, Alden M., Kowalski, Charles J.
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description A review of the dental literature in the United States over the past 60 years is replete with studies utilizing human histological evidence for research. The first reference found for the use of human tissue for histological study was published in 1941 in the Journal of Dental Research.1 Much of this literature focuses on the use of block sections, in which teeth scheduled for extraction are removed along with portions of the surrounding soft tissue and bone in order to study the effects of various interventions. The tissue removed in no way facilitates the surgical extraction of the tooth. It is removed to establish the type of healing, repair, or regeneration by histological evidence. There is no compensating benefit to the patient who, in fact, is put at risk—the removal of the extra tissue may compromise the fit of a subsequent prosthetic restoration. J Periodontol 2005;76:1207‐1210.
doi_str_mv 10.1902/jop.2005.76.7.1207
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source MEDLINE; Access via Wiley Online Library
subjects Dental Research - ethics
Dentistry
Ethics, Research
Histological research
Histology - ethics
Human Experimentation - ethics
Humans
review literature
title Human Histological Research: Is It Necessary? Humane? Ethical?
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