Failure of omalizumab for treatment of severe adult atopic dermatitis

Atopic dermatitis has been associated with elevated levels of IgE. Omalizumab is a monoclonal anti-IgE antibody currently approved for the treatment of asthma. We report the failure of omalizumab to improve atopic dermatitis in 3 patients when administered for 4 months.

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Veröffentlicht in:Journal of the American Academy of Dermatology 2005-08, Vol.53 (2), p.338-340
Hauptverfasser: Krathen, Richard A., Hsu, Sylvia
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container_title Journal of the American Academy of Dermatology
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creator Krathen, Richard A.
Hsu, Sylvia
description Atopic dermatitis has been associated with elevated levels of IgE. Omalizumab is a monoclonal anti-IgE antibody currently approved for the treatment of asthma. We report the failure of omalizumab to improve atopic dermatitis in 3 patients when administered for 4 months.
doi_str_mv 10.1016/j.jaad.2005.02.014
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subjects Adult
Age Factors
Allergic diseases
Antibodies, Anti-Idiotypic
Antibodies, Monoclonal - therapeutic use
Antibodies, Monoclonal, Humanized
Biological and medical sciences
Dermatitis, Atopic - drug therapy
Dermatology
Female
Humans
Immunopathology
Male
Medical sciences
Middle Aged
Omalizumab
Severity of Illness Index
Skin allergic diseases. Stinging insect allergies
Treatment Failure
title Failure of omalizumab for treatment of severe adult atopic dermatitis
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