Failure of omalizumab for treatment of severe adult atopic dermatitis
Atopic dermatitis has been associated with elevated levels of IgE. Omalizumab is a monoclonal anti-IgE antibody currently approved for the treatment of asthma. We report the failure of omalizumab to improve atopic dermatitis in 3 patients when administered for 4 months.
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Veröffentlicht in: | Journal of the American Academy of Dermatology 2005-08, Vol.53 (2), p.338-340 |
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container_title | Journal of the American Academy of Dermatology |
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creator | Krathen, Richard A. Hsu, Sylvia |
description | Atopic dermatitis has been associated with elevated levels of IgE. Omalizumab is a monoclonal anti-IgE antibody currently approved for the treatment of asthma. We report the failure of omalizumab to improve atopic dermatitis in 3 patients when administered for 4 months. |
doi_str_mv | 10.1016/j.jaad.2005.02.014 |
format | Article |
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Omalizumab is a monoclonal anti-IgE antibody currently approved for the treatment of asthma. We report the failure of omalizumab to improve atopic dermatitis in 3 patients when administered for 4 months.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Allergic diseases</subject><subject>Antibodies, Anti-Idiotypic</subject><subject>Antibodies, Monoclonal - therapeutic use</subject><subject>Antibodies, Monoclonal, Humanized</subject><subject>Biological and medical sciences</subject><subject>Dermatitis, Atopic - drug therapy</subject><subject>Dermatology</subject><subject>Female</subject><subject>Humans</subject><subject>Immunopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Omalizumab</subject><subject>Severity of Illness Index</subject><subject>Skin allergic diseases. 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subjects | Adult Age Factors Allergic diseases Antibodies, Anti-Idiotypic Antibodies, Monoclonal - therapeutic use Antibodies, Monoclonal, Humanized Biological and medical sciences Dermatitis, Atopic - drug therapy Dermatology Female Humans Immunopathology Male Medical sciences Middle Aged Omalizumab Severity of Illness Index Skin allergic diseases. Stinging insect allergies Treatment Failure |
title | Failure of omalizumab for treatment of severe adult atopic dermatitis |
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