Streptozotocin-induced diabetic nephropathy in rats: The role of inflammatory cytokines

The role of inflammatory cytokines in the pathogenesis of diabetic nephropathy has been studied in streptozotocin-induced diabetic rats. Rat kidneys were examined by light and electron microscopy and kidney homogenates were also analyzed by Western blot and flow cytometry for the expression of marke...

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Veröffentlicht in:	Cytokine (Philadelphia, Pa.) Pa.), 2005-08, Vol.31 (3), p.180-190
Hauptverfasser:	Mensah-Brown, E.P.K., Obineche, E.N., Galadari, S., Chandranath, E., Shahin, A., Ahmed, I., Patel, S.M., Adem, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Western CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - metabolism CD4-Positive T-Lymphocytes - pathology CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - metabolism CD8-Positive T-Lymphocytes - pathology Cytokines Cytokines - physiology Diabetes Mellitus, Experimental - immunology Diabetes Mellitus, Experimental - metabolism Diabetes Mellitus, Experimental - pathology Diabetic Nephropathies - immunology Diabetic Nephropathies - metabolism Diabetic Nephropathies - pathology Electrophoresis, Polyacrylamide Gel Flow Cytometry Immunohistochemistry Interferon-γ Male Nitric oxide synthase Rats Rats, Wistar Tumor necrosis factor-α Weight Loss - physiology
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