Microwave tumour coagulation plus in situ treatment with cytokine-microparticles: Induction of potent anti-residual tumour immunity

After local microwave coagulation and subsequent intra-tumoural injection of microparticles encapsulating interleukin-2 and granulocyte-macrophage colony-stimulating factor, the anti-tumour efficacy against subcutaneous Lewis lung carcinoma in syngeneic mice was evaluated. This treatment elicited a...

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Veröffentlicht in:	International journal of hyperthermia 2005-05, Vol.21 (3), p.247-257
Hauptverfasser:	Kuang, M., Liu, S. Q., Saijo, K., Uchimura, E., Huang, L., Leong, K.W., Lu, M. D., Huang, J. F., Ohno, T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Cancer Vaccines Carcinoma, Lewis Lung - pathology Carcinoma, Lewis Lung - radiotherapy Carcinoma, Lewis Lung - surgery Cardiology. Vascular system CD3 Complex - immunology Cell Line, Tumor Cytokine Electrocoagulation - methods Female Graft Rejection Granulocyte-Macrophage Colony-Stimulating Factor - genetics Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology Humans immunotherapy in situ vaccination Intensive care medicine Interleukin-2 - genetics Interleukin-2 - pharmacology Killer Cells, Natural - immunology Lung Neoplasms - pathology Lung Neoplasms - radiotherapy Lung Neoplasms - surgery Male Medical sciences Mice Mice, Inbred C57BL Microspheres microwave Microwaves - therapeutic use Neoplasm Transplantation Recombinant Proteins - pharmacology T-Lymphocytes, Cytotoxic - immunology Transfusions. Complications. Transfusion reactions. Cell and gene therapy Tumor Burden tumour coagulation
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