Body-Mass Index and Symptoms of Gastroesophageal Reflux in Women
Obesity is a known risk factor for gastroesophageal reflux disease. Among more than 10,000 women enrolled in the Nurses' Health Study, body-mass index was associated with symptoms of gastroesophageal reflux in both normal-weight and overweight women. Weight gain was associated with symptoms of...
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Veröffentlicht in: | The New England journal of medicine 2006-06, Vol.354 (22), p.2340-2348 |
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creator | Jacobson, Brian C Somers, Samuel C Fuchs, Charles S Kelly, Ciarán P Camargo, Carlos A |
description | Obesity is a known risk factor for gastroesophageal reflux disease. Among more than 10,000 women enrolled in the Nurses' Health Study, body-mass index was associated with symptoms of gastroesophageal reflux in both normal-weight and overweight women. Weight gain was associated with symptoms of reflux, even in women with a normal body-mass index at baseline.
Body-mass index was associated with symptoms of gastroesophageal reflux in both normal-weight and overweight women. Weight gain was associated with symptoms of reflux, even in women with a normal body-mass index at baseline.
Gastroesophageal reflux disease, with hallmark symptoms of heartburn and acid regurgitation,
1
is a common disorder, affecting up to 60 percent of persons at some time during the course of a year and 20 to 30 percent of persons at least weekly.
2
,
3
Gastroesophageal reflux disease accounts for at least 9 million office visits to physicians in the United States each year and costs approximately $10 billion annually.
4
Frequent or severe symptoms of gastroesophageal reflux disease are associated with time lost from work,
5
impaired health-related quality of life,
6
and esophageal adenocarcinoma,
7
further emphasizing the clinical significance of this entity.
Several cross-sectional . . . |
doi_str_mv | 10.1056/NEJMoa054391 |
format | Article |
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Body-mass index was associated with symptoms of gastroesophageal reflux in both normal-weight and overweight women. Weight gain was associated with symptoms of reflux, even in women with a normal body-mass index at baseline.
Gastroesophageal reflux disease, with hallmark symptoms of heartburn and acid regurgitation,
1
is a common disorder, affecting up to 60 percent of persons at some time during the course of a year and 20 to 30 percent of persons at least weekly.
2
,
3
Gastroesophageal reflux disease accounts for at least 9 million office visits to physicians in the United States each year and costs approximately $10 billion annually.
4
Frequent or severe symptoms of gastroesophageal reflux disease are associated with time lost from work,
5
impaired health-related quality of life,
6
and esophageal adenocarcinoma,
7
further emphasizing the clinical significance of this entity.
Several cross-sectional . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMoa054391</identifier><identifier>PMID: 16738270</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Acids ; Adult ; Asthma ; Biological and medical sciences ; Body Mass Index ; Chronic obstructive pulmonary disease ; Cohort Studies ; Digestive system ; Esophagus ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Gastroesophageal Reflux - etiology ; General aspects ; Heartburn - etiology ; Humans ; Lifestyles ; Logistic Models ; Medical sciences ; Middle Aged ; Multivariate Analysis ; Nurses ; Obesity - complications ; Other diseases. Semiology ; Overweight ; Questionnaires ; Risk Factors ; Severity of Illness Index ; Surveys and Questionnaires ; Throat ; Waist-Hip Ratio ; Weight Gain ; Womens health</subject><ispartof>The New England journal of medicine, 2006-06, Vol.354 (22), p.2340-2348</ispartof><rights>Copyright © 2006 Massachusetts Medical Society. All rights reserved.</rights><rights>2006 INIST-CNRS</rights><rights>Copyright 2006 Massachusetts Medical Society.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c570t-50d4ac3e49c7feac0c919979a1c5cf51782fd69e6ce57ad15128114d347abee53</citedby><cites>FETCH-LOGICAL-c570t-50d4ac3e49c7feac0c919979a1c5cf51782fd69e6ce57ad15128114d347abee53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMoa054391$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJMoa054391$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17815560$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16738270$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jacobson, Brian C</creatorcontrib><creatorcontrib>Somers, Samuel C</creatorcontrib><creatorcontrib>Fuchs, Charles S</creatorcontrib><creatorcontrib>Kelly, Ciarán P</creatorcontrib><creatorcontrib>Camargo, Carlos A</creatorcontrib><title>Body-Mass Index and Symptoms of Gastroesophageal Reflux in Women</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>Obesity is a known risk factor for gastroesophageal reflux disease. Among more than 10,000 women enrolled in the Nurses' Health Study, body-mass index was associated with symptoms of gastroesophageal reflux in both normal-weight and overweight women. Weight gain was associated with symptoms of reflux, even in women with a normal body-mass index at baseline.
Body-mass index was associated with symptoms of gastroesophageal reflux in both normal-weight and overweight women. Weight gain was associated with symptoms of reflux, even in women with a normal body-mass index at baseline.
Gastroesophageal reflux disease, with hallmark symptoms of heartburn and acid regurgitation,
1
is a common disorder, affecting up to 60 percent of persons at some time during the course of a year and 20 to 30 percent of persons at least weekly.
2
,
3
Gastroesophageal reflux disease accounts for at least 9 million office visits to physicians in the United States each year and costs approximately $10 billion annually.
4
Frequent or severe symptoms of gastroesophageal reflux disease are associated with time lost from work,
5
impaired health-related quality of life,
6
and esophageal adenocarcinoma,
7
further emphasizing the clinical significance of this entity.
Several cross-sectional . . .</description><subject>Acids</subject><subject>Adult</subject><subject>Asthma</subject><subject>Biological and medical sciences</subject><subject>Body Mass Index</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Cohort Studies</subject><subject>Digestive system</subject><subject>Esophagus</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Gastroesophageal Reflux - etiology</subject><subject>General aspects</subject><subject>Heartburn - etiology</subject><subject>Humans</subject><subject>Lifestyles</subject><subject>Logistic Models</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Nurses</subject><subject>Obesity - complications</subject><subject>Other diseases. Semiology</subject><subject>Overweight</subject><subject>Questionnaires</subject><subject>Risk Factors</subject><subject>Severity of Illness Index</subject><subject>Surveys and Questionnaires</subject><subject>Throat</subject><subject>Waist-Hip Ratio</subject><subject>Weight Gain</subject><subject>Womens health</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpt0MtLw0AQBvBFFK2Pm2cJop6M7mZf2ZsPalWqgg88hnEz0ZRstmYbaP97Iw0o4lzm8uOb4SNkl9ETRqU6vR_e3nmgUnDDVsiASc5jIahaJQNKkzQW2vANshnChHbDhFknG0xpniaaDsjZhc8X8R2EEN3UOc4jqPPoaeGmM-9C5ItoBGHWeAx--gHvCFX0iEXVzqOyjl69w3qbrBVQBdzp9xZ5uRo-X17H44fRzeX5OLZS01ksaS7AchTG6gLBUmuYMdoAs9IWkuk0KXJlUFmUGnImWZIyJnIuNLwhSr5Fjpa508Z_thhmmSuDxaqCGn0bMpVSrrhJOrj_B05829Tdb1mScMOFSk2HjpfINj6EBots2pQOmkXGaPZda_a71o7v9Zntm8P8B_c9duCwBxAsVEUDtS3Dj9Mpk1J9u4Olcy5kNU7c__e-AFOpiVo</recordid><startdate>20060601</startdate><enddate>20060601</enddate><creator>Jacobson, Brian C</creator><creator>Somers, Samuel C</creator><creator>Fuchs, Charles S</creator><creator>Kelly, Ciarán P</creator><creator>Camargo, Carlos A</creator><general>Massachusetts Medical Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20060601</creationdate><title>Body-Mass Index and Symptoms of Gastroesophageal Reflux in Women</title><author>Jacobson, Brian C ; Somers, Samuel C ; Fuchs, Charles S ; Kelly, Ciarán P ; Camargo, Carlos A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c570t-50d4ac3e49c7feac0c919979a1c5cf51782fd69e6ce57ad15128114d347abee53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Acids</topic><topic>Adult</topic><topic>Asthma</topic><topic>Biological and medical sciences</topic><topic>Body Mass Index</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Cohort Studies</topic><topic>Digestive system</topic><topic>Esophagus</topic><topic>Female</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Gastroesophageal Reflux - etiology</topic><topic>General aspects</topic><topic>Heartburn - etiology</topic><topic>Humans</topic><topic>Lifestyles</topic><topic>Logistic Models</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Nurses</topic><topic>Obesity - complications</topic><topic>Other diseases. Semiology</topic><topic>Overweight</topic><topic>Questionnaires</topic><topic>Risk Factors</topic><topic>Severity of Illness Index</topic><topic>Surveys and Questionnaires</topic><topic>Throat</topic><topic>Waist-Hip Ratio</topic><topic>Weight Gain</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jacobson, Brian C</creatorcontrib><creatorcontrib>Somers, Samuel C</creatorcontrib><creatorcontrib>Fuchs, Charles S</creatorcontrib><creatorcontrib>Kelly, Ciarán P</creatorcontrib><creatorcontrib>Camargo, Carlos A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jacobson, Brian C</au><au>Somers, Samuel C</au><au>Fuchs, Charles S</au><au>Kelly, Ciarán P</au><au>Camargo, Carlos A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Body-Mass Index and Symptoms of Gastroesophageal Reflux in Women</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>2006-06-01</date><risdate>2006</risdate><volume>354</volume><issue>22</issue><spage>2340</spage><epage>2348</epage><pages>2340-2348</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>Obesity is a known risk factor for gastroesophageal reflux disease. Among more than 10,000 women enrolled in the Nurses' Health Study, body-mass index was associated with symptoms of gastroesophageal reflux in both normal-weight and overweight women. Weight gain was associated with symptoms of reflux, even in women with a normal body-mass index at baseline.
Body-mass index was associated with symptoms of gastroesophageal reflux in both normal-weight and overweight women. Weight gain was associated with symptoms of reflux, even in women with a normal body-mass index at baseline.
Gastroesophageal reflux disease, with hallmark symptoms of heartburn and acid regurgitation,
1
is a common disorder, affecting up to 60 percent of persons at some time during the course of a year and 20 to 30 percent of persons at least weekly.
2
,
3
Gastroesophageal reflux disease accounts for at least 9 million office visits to physicians in the United States each year and costs approximately $10 billion annually.
4
Frequent or severe symptoms of gastroesophageal reflux disease are associated with time lost from work,
5
impaired health-related quality of life,
6
and esophageal adenocarcinoma,
7
further emphasizing the clinical significance of this entity.
Several cross-sectional . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><pmid>16738270</pmid><doi>10.1056/NEJMoa054391</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine |
subjects | Acids Adult Asthma Biological and medical sciences Body Mass Index Chronic obstructive pulmonary disease Cohort Studies Digestive system Esophagus Female Gastroenterology. Liver. Pancreas. Abdomen Gastroesophageal Reflux - etiology General aspects Heartburn - etiology Humans Lifestyles Logistic Models Medical sciences Middle Aged Multivariate Analysis Nurses Obesity - complications Other diseases. Semiology Overweight Questionnaires Risk Factors Severity of Illness Index Surveys and Questionnaires Throat Waist-Hip Ratio Weight Gain Womens health |
title | Body-Mass Index and Symptoms of Gastroesophageal Reflux in Women |
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