Effect of buformin and metformin on formation of advanced glycation end products by methylglyoxal

The formation and accumulation of advanced glycation end products (AGE) in various tissues are known to be involved in the aging process and complications of long-term diabetes. Aminoguanidine as AGE inhibitors was first studied, and metformin as biguanide compounds have been reported to react with...

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Veröffentlicht in:	Clinica chimica acta 2005-08, Vol.358 (1), p.139-145
Hauptverfasser:	Kiho, Tadashi, Kato, Motohiro, Usui, Shigeyuki, Hirano, Kazuyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced glycation end products Animals Buformin Buformin - chemistry Cattle Enzyme-Linked Immunosorbent Assay Glycation Glycation End Products, Advanced - analysis Glycation End Products, Advanced - chemical synthesis Guanidines - chemistry Inhibition Metformin Metformin - chemistry Methylglyoxal Pyruvaldehyde - chemistry Ribonucleases - chemistry Ribonucleases - pharmacology Serum Albumin, Bovine - chemistry Time Factors
Online-Zugang:	Volltext
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