New Amides of 5-Acylamino-3-Methyl-4-Isothiazolecarboxylic Acid and their Immunotropic Activity

Several new amides 4 of 5‐substituted 3‐methyl‐4‐isothiazolecarboxylic acid were obtained. These compounds have acetylamino or benzoylamino groups in position 5 of the isothiazole ring. In position 4, the carboxylic group was transformed in the amides using amino‐acid esters. Activities of the obtai...

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Veröffentlicht in:	Archiv der Pharmazie (Weinheim) 2005-07, Vol.338 (7), p.322-328
Hauptverfasser:	Lipnicka, Urszula, Regiec, Andrzej, Sułkowski, Emil, Zimecki, Michał
Format:	Artikel
Sprache:	eng
Schlagworte:	5-amino-3-methylisothiazolecarboxamides Amides - chemical synthesis Amides - immunology Amides - pharmacology Animals Antibody Formation - drug effects Antibody Formation - immunology Cell Proliferation - drug effects Chemistry, Pharmaceutical - methods Chemistry, Pharmaceutical - trends Erythrocytes - drug effects Erythrocytes - immunology Hypersensitivity, Delayed - drug therapy Hypersensitivity, Delayed - immunology Immunotropic activity Male Mice Mice, Inbred CBA Sheep Spleen - cytology Synthesis Thiazoles - chemical synthesis Thiazoles - immunology Thiazoles - pharmacology
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