Procolipase gene expression in the rat brain: Source of endogenous enterostatin production in the brain

Enterostatin is a pentapeptide released from its precursor protein procolipase, which is synthesized in the exocrine pancreas and gastric mucosa. As central injection of enterostatin has potent effects on feeding, we hypothesized that the procolipase may also be expressed in the brain. We confirmed...

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Veröffentlicht in:	Brain research 2006-05, Vol.1087 (1), p.52-59
Hauptverfasser:	York, David A., Lin, Ling, Thomas, Sonjya R., Braymer, Hugh D., Park, MieJung
Format:	Artikel
Sprache:	eng
Schlagworte:	Amygdala Analysis of Variance Animals Antibodies - pharmacology Behavior, Animal Biochemistry and metabolism Biological and medical sciences Blotting, Northern - methods Blotting, Western - methods Brain - physiology Central nervous system Colipases - genetics Colipases - immunology Colipases - metabolism Eating - drug effects Eating - physiology Enzyme Precursors Fundamental and applied biological sciences. Psychology Gene Expression - physiology Hypothalamus Immunohistochemistry Immunohistochemistry - methods Male Northern blot Protein Precursors - genetics Protein Precursors - immunology Protein Precursors - metabolism Rats Reverse Transcriptase Polymerase Chain Reaction - methods RNA, Messenger - metabolism RT-PCR Vertebrates: nervous system and sense organs Western blot
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