P53 Gene Status in Patients with Advanced Serous Epithelial Ovarian Cancer in Relation to Response to Paclitaxel- plus Platinum-based Chemotherapy and Long-term Clinical Outcome

Background: The aim of this retrospective study was to assess whether p53 gene status has any predictive or prognostic relevance in patients with advanced, poorly-differentiated serous epithelial ovarian cancer treated with paclitaxel- plus platinum-based chemotherapy. Materials and Methods: The stu...

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Veröffentlicht in:	Anticancer research 2006-01, Vol.26 (1B), p.687-693
Hauptverfasser:	GADDUCCI, Angiolo, DI CRISTOFANO, Claudio, ZAVAGLIA, Michele, GIUSTI, Laura, MENICAGLI, Michele, COSIO, Stefania, NACCARATO, Antonio G, GENAZZANI, Andrea R, BEVILACQUA, Generoso, CAVAZZANA, Andrea O
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Cystadenocarcinoma, Serous - drug therapy Cystadenocarcinoma, Serous - genetics Cystadenocarcinoma, Serous - pathology Disease-Free Survival Exons Female Female genital diseases Genes, p53 Gynecology. Andrology. Obstetrics Humans Immunohistochemistry Medical sciences Middle Aged Neoplasm Staging Organoplatinum Compounds - administration & dosage Ovarian Neoplasms - drug therapy Ovarian Neoplasms - genetics Ovarian Neoplasms - pathology Paclitaxel - administration & dosage Polymorphism, Genetic Treatment Outcome Tumors
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