Use of vancomycin chiral stationary phase for the enantiomeric resolution of basic and acidic compounds by nano-liquid chromatography

In this paper we studied the potentiality of nano-liquid chromatography (nano-LC) for the enantiomeric resolution of both basic and acidic compounds of pharmaceutical interest using a vancomycin modified silica stationary phase. Experiments were carried out in a fused silica capillary of 75 μm I.D....

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Veröffentlicht in:	Journal of Chromatography A 2005-07, Vol.1081 (1), p.105-113
Hauptverfasser:	D’Orazio, G., Aturki, Z., Cristalli, M., Quaglia, M.G., Fanali, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic beta-Antagonists - isolation & purification Alprenolol - isolation & purification Analysis Atenolol - isolation & purification Biological and medical sciences Chiral Chromatography, Liquid - methods Drugs Enantiomers General pharmacology Medical sciences Metoprolol - isolation & purification Nano-liquid chromatography Nanotechnology - methods Pharmaceutical Preparations - isolation & purification Pharmacology. Drug treatments Pindolol - isolation & purification Stereoisomerism Vancomycin Vancomycin - chemistry
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