[5C + 1N] annulation: a novel synthetic strategy for functionalized 2,3-dihydro-4-pyridones

A novel and facile route to functionalized mono/bicyclic 2,3-dihydro-4-pyridones has been developed via formal [5C + 1N] annulation of readily available alpha-alkenoyl ketene-(S,S)-acetals with various aliphatic primary amines.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2005-01 (28), p.3580-3582
Hauptverfasser: Dong, Dewen, Bi, Xihe, Liu, Qun, Cong, Fangdi
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container_title Chemical communications (Cambridge, England)
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creator Dong, Dewen
Bi, Xihe
Liu, Qun
Cong, Fangdi
description A novel and facile route to functionalized mono/bicyclic 2,3-dihydro-4-pyridones has been developed via formal [5C + 1N] annulation of readily available alpha-alkenoyl ketene-(S,S)-acetals with various aliphatic primary amines.
doi_str_mv 10.1039/b505569e
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source Royal Society of Chemistry Journals Archive (1841-2007); Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
title [5C + 1N] annulation: a novel synthetic strategy for functionalized 2,3-dihydro-4-pyridones
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