High frequency and strong prognostic relevance of O6-methylguanine DNA methyltransferase silencing in diffuse large B-cell lymphomas from the Middle East

Several clinically relevant molecular classifiers of diffuse large B-cell lymphoma (DLBCL) have recently been demonstrated in Western populations. However, substantial molecular differences have recently been shown between tumors derived from different ethnic groups. To investigate prevalence and in...

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Veröffentlicht in:	Human pathology 2006-06, Vol.37 (6), p.742-748
Hauptverfasser:	AL-KURAYA, Khawla, NARAYANAPPA, Rajeswari, ABDUL KHALID SIRAJ, AL-DAYEL, Fouad, EZZAT, Adnan, EL SOLH, Hassan, AL-JOMMAH, Naif, SAUTER, Guido, SIMON, Ronald
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chromosomes, Human, Pair 14 Chromosomes, Human, Pair 18 DNA Methylation Follow-Up Studies Gene Silencing Humans Immunohistochemistry In Situ Hybridization, Fluorescence Investigative techniques, diagnostic techniques (general aspects) Lymphoma, B-Cell - genetics Lymphoma, B-Cell - metabolism Lymphoma, B-Cell - mortality Lymphoma, Large B-Cell, Diffuse - genetics Lymphoma, Large B-Cell, Diffuse - metabolism Lymphoma, Large B-Cell, Diffuse - mortality Medical sciences Neprilysin - analysis O-Methylguanine-DNA Methyltransferase - genetics O-Methylguanine-DNA Methyltransferase - metabolism Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Prognosis Saudi Arabia Survival Analysis Translocation, Genetic
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