Central Relaxin-3 Administration Causes Hyperphagia in Male Wistar Rats

Relaxin-3 (INSL-7) is a recently discovered member of the insulin superfamily. Relaxin-3 mRNA is expressed in the nucleus incertus of the brainstem, which has projections to the hypothalamus. Relaxin-3 binds with high affinity to the LGR7 receptor and to the previously orphan G protein-coupled recep...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2005-08, Vol.146 (8), p.3295-3300
Hauptverfasser:	McGowan, B. M. C, Stanley, S. A, Smith, K. L, White, N. E, Connolly, M. M, Thompson, E. L, Gardiner, J. V, Murphy, K. G, Ghatei, M. A, Bloom, S. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Brain stem Central nervous system Cerebral Ventricles - drug effects Cerebral Ventricles - physiology Feeding behavior Food Food intake Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation - drug effects Hyperphagia Hyperphagia - chemically induced Hypothalamus Hypothalamus - physiopathology Injections, Intraventricular Male Males Midline Thalamic Nuclei - drug effects Midline Thalamic Nuclei - physiology Neuropeptide Y Neuropeptide Y - genetics Paraventricular nucleus Pro-Opiomelanocortin - genetics Proopiomelanocortin Rats Rats, Wistar Receptors Relaxin Relaxin - administration & dosage Relaxin - pharmacology RNA, Messenger - genetics Vertebrates: endocrinology
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