Interchromosomal segmental duplications explain the unusual structure of PRSS3, the gene for an inhibitor-resistant trypsinogen

Homo sapiens possess several trypsinogen or trypsinogen-like genes of which three (PRSS1, PRSS2, and PRSS3) produce functional trypsins in the digestive tract. PRSS1 and PRSS2 are located on chromosome 7q35, while PRSS3 is found on chromosome 9p13. Here, we report a variation of the theme of new gen...

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Veröffentlicht in:	Molecular biology and evolution 2005-08, Vol.22 (8), p.1712-1720
Hauptverfasser:	Rowen, Lee, Williams, Eleanor, Glusman, Gustavo, Linardopoulou, Elena, Friedman, Cynthia, Ahearn, Mary Ellen, Seto, Jason, Boysen, Cecilie, Qin, Shizhen, Wang, Kai, Kaur, Amardeep, Bloom, Scott, Hood, Leroy, Trask, Barbara J
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromosomes, Human - genetics Evolution, Molecular Exons - genetics Humans Quantitative Trait Loci - genetics Selection, Genetic Trypsin - genetics Trypsin Inhibitors - genetics Trypsinogen - genetics
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