Gene therapy of the ischemic lower limb — Therapeutic angiogenesis

The limitations of surgical revascularisation and pharmacological treatment in peripheral arterial occlusive disease (PAOD) are well recognized. Therapeutic options for critical leg ischemia are consequently limited to percutaneous transluminal angioplasty (PTA) or surgical revascularisation. Unfort...

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Veröffentlicht in:	Vascular pharmacology 2006-06, Vol.44 (6), p.395-405
Hauptverfasser:	Bobek, Vladimir, Taltynov, Oliver, Pinterova, Daniela, Kolostova, Katarina
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arterial Occlusive Diseases - metabolism Arterial Occlusive Diseases - therapy Clinical Trials as Topic Endothelial Cells - metabolism Endothelial Cells - transplantation Gene Transfer Techniques Genetic Therapy - trends Genetic Vectors Humans Ischemia - metabolism Ischemia - therapy Lower Extremity - blood supply Models, Animal Neovascularization, Physiologic PAOD Plasmid Therapeutic angiogenesis Vascular Endothelial Growth Factors - genetics Vascular Endothelial Growth Factors - metabolism Vector VEGF
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